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Nuca Gene Detail
Summary
  • Symbol
    Nuca
  • Name
    dominant nuclear cataract
  • Feature Type
    heritable phenotypic marker
  • IDs
    MGI:97387
    NCBI Gene: 104352
  • Alliance
Location & Maps
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  • Sequence Map
    Genome coordinates not available
  • Genetic Map
    Chromosome Unknown
Human Diseases
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  • Diseases
    1 with Nuca mouse models

Human Disease Mouse Models
      
IDs
View 1 model
Click on a disease name to see all genes associated with that disease.

  • Mutations/Alleles
    1 with disease annotations
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    5 phenotypes from 1 allele in 1 genetic background
    2 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Heterozygotes exhibit opacities of the embryonic lens nucleus and the posterior embryonic suture. Most are also sterile and those that are fertile have reduced litter size. Homozygotes die prenatally.
Sequences &
Gene Models
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Other
Accession IDs
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MGD-MRK-12948
References
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  • Summaries
    All 3
    Diseases 1
    Phenotypes 2
  • Earliest
    J:6686 Kratochvilova J, Dominant cataract mutations detected in offspring of gamma-irradiated male mice. J Hered. 1981 Sep-Oct;72(5):302-7
  • Latest
    J:9528 Kratochvilova J, et al., Phenotypic characterization and genetic analysis of twenty dominant cataract mutations detected in offspring of irradiated male mice. Genet Res. 1988 Oct;52(2):125-34

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
12/13/2017
MGI 6.11
The Jackson Laboratory