About   Help   FAQ
Mdac Gene Detail
Summary
  • Symbol
    Mdac
  • Name
    modifier of Dac
  • Feature Type
    heritable phenotypic marker
  • IDs
    MGI:96947
    NCBI Gene: 17238
Location & Maps
more
  • Genetic Map
    Chromosome 13, Syntenic
  • Mapping Data
    2 experiments
Human Diseases
less
  • Mutations/Alleles
    1 with disease annotations
  • References
    2 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    13 phenotypes from multigenic genotypes
    5 phenotype references
  • All Mutations and Alleles
    2
  • Spontaneous
    2
Mice homozygous for the recessive mdac allele alone display no visible phenotype. However, the dominant allele, Mdac, interacts with the Dac gene to suppress the severity of the digit dysmorphology in Dac heterozygotes and embryonic lethality in Dac homozygotes.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Sequences &
Gene Models
less
Other
Accession IDs
less
MGD-MRK-12161
References
more
  • Summaries
    All 6
    Diseases 2
    Gene Ontology 1
    Phenotypes 5
  • Earliest
    J:6607 Chai CK, Dactylaplasia in mice a two-locus model for development anomalies. J Hered. 1981 Jul-Aug;72(4):234-7
  • Latest
    J:127601 Kano H, et al., Genetically regulated epigenetic transcriptional activation of retrotransposon insertion confers mouse dactylaplasia phenotype. Proc Natl Acad Sci U S A. 2007 Nov 27;104(48):19034-9

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
09/13/2016
MGI 6.05
The Jackson Laboratory