About   Help   FAQ
Mdac
Gene Detail
Symbol

Name
ID
Mdac
modifier of Dac
MGI:96947
Feature Type
heritable phenotypic marker
Genetic Map
Chromosome 13
Syntenic

Mapping data(2)
Sequence Map
Chr13:56127983-64961758 bp
From MGI annotation of GRCm38

  8833776 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Mutations,
alleles, and
phenotypes
All mutations/alleles(2) : Spontaneous(2)
 
Mice homozygous for the recessive mdac allele alone display no visible phenotype. However, the dominant allele, Mdac, interacts with the Dac gene to suppress the severity of the digit dysmorphology in Dac heterozygotes and embryonic lethality in Dac homozygotes.
 
Alleles Annotated to Human Diseases(1)   
Gene Ontology
(GO)
classifications
All GO classifications: (1 annotations)
Process limb development
Other database
links
Entrez Gene17238
References
(Earliest) J:6607 Chai CK, Dactylaplasia in mice a two-locus model for development anomalies. J Hered. 1981 Jul-Aug;72(4):234-7
(Latest) J:127601 Kano H, et al., Genetically regulated epigenetic transcriptional activation of retrotransposon insertion confers mouse dactylaplasia phenotype. Proc Natl Acad Sci U S A. 2007 Nov 27;104(48):19034-9
All references(6)
Other
accession IDs
MGD-MRK-12161

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
12/09/2014
MGI 5.20
The Jackson Laboratory