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Lamp1 Gene Detail
Summary
  • Symbol
    Lamp1
  • Name
    lysosomal-associated membrane protein 1
  • Synonyms
    CD107a, Lamp-1
  • Feature Type
    protein coding gene
  • IDs
    MGI:96745
    NCBI Gene: 16783
  • Gene Overview
    MyGene.info: LAMP1
Location & Maps
more
  • Sequence Map
    Chr8:13159135-13175338 bp, + strand
  • From Ensembl annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      16204 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 8, 5.73 cM
  • Mapping Data
    4 experiments
Homology
more
  • Human Ortholog
    LAMP1, lysosomal associated membrane protein 1
  • Vertebrate Orthologs
    9
  • Human Ortholog
    LAMP1, lysosomal associated membrane protein 1
    Orthology source: HGNC, HomoloGene
  • Synonyms
    CD107a, LAMPA, LGP120
  • Links
    NCBI Gene ID: 3916
    neXtProt AC: NX_P11279

  • Chr Location
    13q34; chr13:113297121-113323431 (+)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    10 phenotypes from multigenic genotypes
    10 phenotype references
Mice homozygous for disruptions in this gene display a normal phenotype.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000031447 Ensembl Gene Model | MGI Sequence Detail 16204 C57BL/6J ±  kb
transcript ENSMUST00000033824 Ensembl | MGI Sequence Detail 2255 Not Applicable  
polypeptide ENSMUSP00000033824 Ensembl | MGI Sequence Detail 406 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    123 from dbSNP Build 142
  • PCR
Protein
Information
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  • UniProt
    6 Sequences
  • Protein Ontology
    PR:000002060 lysosome-associated membrane glycoprotein 1
  • InterPro Domains
    IPR002000 Lysosome-associated membrane glycoprotein
    IPR018134 Lysosome-associated membrane glycoprotein, conserved site
Molecular
Reagents
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  • All nucleic 478
    cDNA 475
    Primer pair 2
    Other 1

    Microarray probesets 3
Other
Accession IDs
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MGD-MRK-11740, MGD-MRK-11742, MGI:2142479
References
more
  • Summaries
    All 136
    Developmental Gene Expression 32
    Gene Ontology 37
    Phenotypes 10
  • Earliest
    J:8849 Green SA, et al., Kinetics of intracellular transport and sorting of lysosomal membrane and plasma membrane proteins. J Cell Biol. 1987 Sep;105(3):1227-40
  • Latest
    J:228212 Cinque L, et al., FGF signalling regulates bone growth through autophagy. Nature. 2015 Dec 10;528(7581):272-5

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/19/2016
MGI 6.04
The Jackson Laboratory