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In(15)4H Cytogenetic Marker Detail
Summary
  • Symbol
    In(15)4H
  • Name
    inversion, Chr 15, Harwell 4
  • Synonyms
    Koa, koala
  • Feature Type
    chromosomal inversion
  • IDs
    MGI:96678
    NCBI Gene: 109551
Location & Maps
more
  • Sequence Map
    Genome coordinates not available
  • Genetic Map
    Chromosome 15, Syntenic
  • Mapping Data
    3 experiments
Human Diseases
more
  • Diseases
    1 with In(15)4H mouse models

Human Disease Mouse Models
       Hypertrichosis Universalis Congenita, Ambras Type; HTC1   OMIM: 145701 View 2 models
Click on a disease name to see all genes associated with that disease.

  • Mutations/Alleles
    1 with disease annotations
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    10 phenotypes from 1 allele in 2 genetic backgrounds
    6 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    1
  • Radiation induced
    1
Homozygotes have long hair on the ears and a bushy muzzle. They have a broader head, open eyes at birth, smaller body size and smaller litters. Heterozygotes also have longer hair on the ears and a bushy muzzle.
Sequences &
Gene Models
less
Other
Accession IDs
less
MGD-MRK-11594
References
more
  • Summaries
    All 8
    Diseases 1
    Phenotypes 6
  • Earliest
    J:14236 Ball ST, et al., Koala, a dominant mutation. Mouse News Lett. 1989;83:163-4
  • Latest
    J:155838 Katayama K, et al., Characterization of the chromosomal inversion associated with the Koa mutation in the mouse revealed the cause of skeletal abnormalities. BMC Genet. 2009;10:60

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/22/2016
MGI 6.06
The Jackson Laboratory