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Igk-J Complex/Cluster/Region Detail
Summary
  • Symbol
    Igk-J
  • Name
    immunoglobulin kappa chain, joining region
  • Feature Type
    complex/cluster/region
  • IDs
    MGI:96497
    NCBI Gene: 16073
Location & Maps
more
  • Sequence Map
    Genome coordinates not available
  • Genetic Map
    Chromosome 6, Syntenic
  • Mapping Data
    9 experiments
Human Diseases
less
  • Mutations/Alleles
    1 with disease annotations
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    8 phenotypes from 3 alleles in 2 genetic backgrounds
    16 phenotypes from multigenic genotypes
    31 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryogenesis
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
tumorigenesis
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    9
  • Targeted
    9
Mice homozygous for various knock-in alleles exhibit abnormal immune system morphology and function.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Other Mouse Links
Sequences &
Gene Models
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  • All Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic M15559 GenBank | EMBL | DDBJ | MGI Sequence Detail 1430 C.C58 M75* ±  kb
For the selected sequence
Polymorphisms
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  • RFLP
Molecular
Reagents
less
  • All nucleic 120
    Genomic 53
    cDNA 62
    Other 5
Other
Accession IDs
less
MGD-MRK-11296
References
more
  • Summaries
    All 81
    Developmental Gene Expression 1
    Diseases 1
    Phenotypes 31
  • Earliest
    J:6069 Seidman JG, et al., The arrangement and rearrangement of antibody genes. Nature. 1978 Dec 21-28;276(5690):790-5
  • Latest
    J:211640 Park SK, et al., Pronounced cohabitation of active immunoglobulin genes from three different chromosomes in transcription factories during maximal antibody synthesis. Genes Dev. 2014 Jun 1;28(11):1159-64

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
02/02/2016
MGI 6.02
The Jackson Laboratory