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Hoxa
Complex/Cluster/Region Detail
Symbol

Name
ID
Cluster members
Hoxa
homeobox A cluster
MGI:96169
Hoxa1, Hoxa2, Hoxa3 ... (11 members)
Synonyms
Hox-1
Feature Type
complex/cluster/region
Genetic Map
Chromosome 6
cytoband B3-C

Mapping data(18)
Mutations,
alleles, and
phenotypes
All mutations/alleles(2) : Targeted(2)
 
Mice homozygous for mutations in multiple members of the cluster display a range of phenotypes including prenatal and postnatal lethality and developmental defects in the skeletal, reproductive nervous, cardiovascular, digestive, immune, glandular and renal/urinary systems.
 
Interactions
Hoxa interacts with 2 markers (Mir181a-1, Mir181a-2)
Molecular
reagents
All nucleic(6) Genomic(6)
Other database
links
Entrez Gene111336
Polymorphisms
RFLP(3) : SNPs within 2kb(0 from dbSNP Build 137)
References
(Earliest) J:7440 McGinnis W, et al., A homologous protein-coding sequence in Drosophila homeotic genes and its conservation in other metazoans. Cell. 1984 Jun;37(2):403-8
(Latest) J:207500 Berlivet S, et al., Clustering of tissue-specific sub-TADs accompanies the regulation of HoxA genes in developing limbs. PLoS Genet. 2013 Dec;9(12):e1004018
All references(55)
Other
accession IDs
MGD-MRK-10814, MGD-MRK-10870

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
10/08/2014
MGI 5.20
The Jackson Laboratory