Hoxa
Complex/Cluster/Region Detail

Symbol

Name
ID
Cluster members

Hoxa
homeobox A cluster
MGI:96169
Hoxa1, Hoxa2, Hoxa3 ... (11 members)

Synonyms

Hox-1

Feature Type

complex/cluster/region

Genetic Map

Chromosome 6
cytoband B3-C

Mapping data(18)

Mutations,
alleles, and
phenotypes

All mutations/alleles(2) : Targeted(2)
 

Mice homozygous for mutations in multiple members of the cluster display a range of phenotypes including prenatal and postnatal lethality and developmental defects in the skeletal, reproductive nervous, cardiovascular, digestive, immune, glandular and renal/urinary systems.

 

Interactions

Hoxa interacts with 2 markers (Mir181a-1, Mir181a-2)

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Molecular
reagents

All nucleic(6) Genomic(6)

Other database
links

Entrez Gene

111336

Polymorphisms

RFLP(3) : SNPs within 2kb(0 from dbSNP Build 137)

References

(Earliest) J:7440 McGinnis W, et al., A homologous protein-coding sequence in Drosophila homeotic genes and its conservation in other metazoans. Cell. 1984 Jun;37(2):403-8
(Latest) J:207500 Berlivet S, et al., Clustering of tissue-specific sub-TADs accompanies the regulation of HoxA genes in developing limbs. PLoS Genet. 2013 Dec;9(12):e1004018
All references(55)

Other
accession IDs

MGD-MRK-10814, MGD-MRK-10870

Hoxa Cluster contains:

More Data for these features

Member	Feature Type	Location
Hoxa1, homeobox A1	protein coding gene	Chr6:52155590-52158317 (-)
Hoxa2, homeobox A2	protein coding gene	Chr6:52162511-52164831 (-)
Hoxa3, homeobox A3	protein coding gene	Chr6:52169062-52213336 (-)
Hoxa4, homeobox A4	protein coding gene	Chr6:52189671-52191753 (-)
Hoxa5, homeobox A5	protein coding gene	Chr6:52201754-52204587 (-)
Hoxa6, homeobox A6	protein coding gene	Chr6:52206288-52208722 (-)
Hoxa7, homeobox A7	protein coding gene	Chr6:52214491-52221854 (-)
Hoxa9, homeobox A9	protein coding gene	Chr6:52223100-52231089 (-)
Hoxa10, homeobox A10	protein coding gene	Chr6:52231197-52240854 (-)
Hoxa11, homeobox A11	protein coding gene	Chr6:52242106-52245810 (-)
Hoxa13, homeobox A13	protein coding gene	Chr6:52257694-52260803 (-)