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H2-M2 Gene Detail
Summary
  • Symbol
    H2-M2
  • Name
    histocompatibility 2, M region locus 2
  • Synonyms
    H-2M2, Thy19.4
  • Feature Type
    protein coding gene
  • IDs
    MGI:95914
    NCBI Gene: 14990
  • Alliance
    gene page
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr17:37480851-37483552 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 17, 19.16 cM
  • Mapping Data
    9 experiments
  • Sequence Tag
    D17Mit24
Strain
Comparison
more
  • Strain Annotations
    17
  • RFLP
    4
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_95914
 protein coding gene Chr17:37480851-37483554 (-)
129S1/SvImJ MGP_129S1SvImJ_G0023714
 protein coding gene Chr17:37887793-37890489 (-)
A/J MGP_AJ_G0023672
 protein coding gene Chr17:36722826-36725527 (-)
AKR/J MGP_AKRJ_G0023643
 protein coding gene Chr17:37144109-37146819 (-)
BALB/cJ MGP_BALBcJ_G0023678
 protein coding gene Chr17:36936001-36938709 (-)
C3H/HeJ MGP_C3HHeJ_G0023440
 protein coding gene Chr17:37685984-37688694 (-)
C57BL/6NJ MGP_C57BL6NJ_G0024116
 protein coding gene Chr17:39504762-39507463 (-)
CAROLI/EiJ no annotation
CAST/EiJ MGP_CASTEiJ_G0022926
 protein coding gene Chr17:37770808-37773584 (-)
CBA/J MGP_CBAJ_G0023417
 protein coding gene Chr17:41063223-41065933 (-)
DBA/2J MGP_DBA2J_G0023543
 protein coding gene Chr17:36066085-36068789 (-)
FVB/NJ MGP_FVBNJ_G0023516
 protein coding gene Chr17:35683159-35685859 (-)
LP/J MGP_LPJ_G0023621
 protein coding gene Chr17:38455166-38457842 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0023539
 protein coding gene Chr17:39861667-39864368 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0024162
 protein coding gene Chr17:37493062-37495766 (-)
PWK/PhJ MGP_PWKPhJ_G0022673
 protein coding gene Chr17:34843466-34846273 (-)
SPRET/EiJ MGP_SPRETEiJ_G0022494
 protein coding gene Chr17:35570121-35573248 (-)
WSB/EiJ MGP_WSBEiJ_G0022990
 protein coding gene Chr17:37837148-37839822 (-)



Homology
less
Mutations,
Alleles, and
Phenotypes
less
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    11
  • GO References
    2
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    24
  • Tissues
    20
  • cDNA Data
    6
  • Literature Summary
    2
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000016283 Ensembl Gene Model | MGI Sequence Detail 2702 C57BL/6J ±  kb
transcript ENSMUST00000171139 Ensembl | MGI Sequence Detail 1298 Not Applicable  
polypeptide ENSMUSP00000131297 Ensembl | MGI Sequence Detail 343 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    6 Sequences
  • InterPro Domains
    IPR003597 Immunoglobulin C1-set
    IPR007110 Immunoglobulin-like domain
    IPR036179 Immunoglobulin-like domain superfamily
    IPR013783 Immunoglobulin-like fold
    IPR003006 Immunoglobulin/major histocompatibility complex, conserved site
    IPR011162 MHC classes I/II-like antigen recognition protein
    IPR001039 MHC class I alpha chain, alpha1 alpha2 domains
    IPR011161 MHC class I-like antigen recognition-like
    IPR037055 MHC class I-like antigen recognition-like superfamily
Molecular
Reagents
less
  • All nucleic 17
    Genomic 9
    cDNA 6
    Primer pair 1
    Other 1

    Microarray probesets 2
Other
Accession IDs
less
MGD-MRK-10399, MGD-MRK-10510, MGD-MRK-15103
References
more
  • Summaries
    All 28
    Developmental Gene Expression 2
    Gene Ontology 2
  • Earliest
    J:10054 Brorson KA, et al., Analysis of a new class I gene mapping to the Hmt region of the mouse. Immunogenetics. 1989;30(4):273-83
  • Latest
    J:265628 Gaudet P, et al., Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief Bioinform. 2011 Sep;12(5):449-62
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
02/11/2020
MGI 6.14 		The Jackson Laboratory