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Symbol Name ID |
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| Synonyms | H-2, MHC-II | ||
| Feature Type | complex/cluster/region | ||
| Genetic Map | |||
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Alleles and phenotypes |
All alleles(15) :
Targeted(1)
Spontaneous(1)
Other(13)
The H2 complex contains 3 major classes of highly polymorphic gene sets: class I (H2-K, H2-D, Q, H2-T18 genes), class II (H2-I genes), and class III (H2-S genes). These genes are involved in many processes, including graft rejection, immune response, antigen presentation and complement component. Alleles Annotated to Human Diseases(3) Phenotype Images(2) |
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| Expression |
Literature Summary: (5 records) cDNA source data(5) |
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Molecular reagents |
All nucleic(10)
cDNA(8)
Other(2)
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Other database links |
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| Polymorphisms | RFLP(12) : SNPs(0 from dbSNP Build 128) | ||
| References |
(Earliest) J:301
Snell GD, Preliminary data on crossing-over between H-2, and Fu, Ki and T in the mouse. Heredity. 1952;6:247-54 (Latest) J:195514 Smyth LA, et al., Tolerogenic Donor-Derived Dendritic Cells Risk Sensitization In Vivo owing to Processing and Presentation by Recipient APCs. J Immunol. 2013 May 1;190(9):4848-60 All references(565) |
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Other accession IDs |
MGD-MRK-10366, MGD-MRK-10489 |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc |
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last database update 06/05/2013 MGI 5.13 |
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