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H1f0
Gene Detail
Symbol

Name
ID
H1f0
H1 histone family, member 0
MGI:95893
Synonyms
D130017D06Rik, H1fv
Feature Type
protein coding gene
Genetic Map
Chromosome 15
37.70 cM
Detailed Genetic Map ± 1 cM


Mapping data(7)
Sequence Map
Chr15:79028212-79030498 bp, + strand
From Ensembl annotation of GRCm38

  2287 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:136788  Vertebrate Homology Class
1 human; 1 mouse; 1 chimpanzee; 1 rhesus macaque

Protein SuperFamily: histone H1
Gene Tree: H1f0

Human
homologs
Human Homolog H1F0, H1 histone family, member 0
NCBI Gene ID 3005
neXtProt AC  NX_P07305
Human Synonyms  H10, H1FV
Human Chr (Location)  22q13.1; chr22:37805107-37807436 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(3) : Gene trapped(1) Radiation induced(1) Targeted(1)
Genomic Mutations involving H1f0 (1)
 
Mice homozygous for a knock-out allele are viable, fertile and overtly normal with no apparent anatomic or histologic abnormalities or defects in cell division patterns.
 
Interactions
H1f0 interacts with 220 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (14 annotations)
Process nucleosome assembly
Component actin cytoskeleton, chromosome, ...
Function chromatin DNA binding, DNA binding, ...
External Resources: FuncBase
Expression
Literature Summary: (4 records)
Data Summary: Results (13)    Tissues (12)    Images (1)    Tissue x Stage Matrix (view)
Assay TypeResults
Immunohistochemistry 5
RNA in situ 1
RT-PCR 7
cDNA source data(18)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(23) Genomic(3) cDNA(18) Primer pair(2)
Microarray probesets(4)
Other database
links
Ensembl Gene ModelENSMUSG00000096210 (Evidence)
Entrez Gene14958 (Evidence)
DFCITC1573923, TC1608006
Consensus CDS ProjectCCDS56990.1
International Mouse Knockout Project StatusH1f0
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000096210 Ensembl Gene Model | MGI Sequence Detail 2287 C57BL/6J ±  kb
transcript ENSMUST00000180086 Ensembl | MGI Sequence Detail 2287 Not Applicable 
polypeptide ENSMUSP00000137309 Ensembl | MGI Sequence Detail 194 Not Applicable 

For the selected sequences
All sequences(35) RefSeq(2) UniProt(4)
Polymorphisms
All PCR and RFLP(2) : PCR(1) RFLP(1) SNPs within 2kb(3 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR005818 Histone H1/H5
InterPro IPR005819 Histone H5
InterPro IPR013783 Immunoglobulin-like fold
InterPro IPR013768 Intercellular adhesion molecule, N-terminal
InterPro IPR011991 Winged helix-turn-helix DNA-binding domain
Protein Ontology PR:000008405 histone H1.0
References
(Earliest) J:16829 Alonso A, et al., Early increase in histone H1(0) mRNA during differentiation of F9 cells to parietal endoderm. EMBO J. 1988 Oct;7(10):3003-8
(Latest) J:207809 Hayakawa K, et al., Oocyte-specific linker histone H1foo is an epigenomic modulator that decondenses chromatin and impairs pluripotency. Epigenetics. 2012 Sep;7(9):1029-36
All references(52)
Other
accession IDs
MGD-MRK-10488, MGI:2444656

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
10/08/2014
MGI 5.20
The Jackson Laboratory