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H19
Gene Detail
Symbol

Name
ID
H19
H19, imprinted maternally expressed transcript
MGI:95891
Feature Type
lincRNA gene
Genetic Map
Chromosome 7
87.97 cM
Detailed Genetic Map ± 1 cM


Mapping data(38)
Sequence Map
Chr7:142575529-142578143 bp, - strand
From VEGA annotation of GRCm38

  2615 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
Gene Tree: H19
Mutations,
alleles, and
phenotypes
All mutations/alleles(10) : Targeted(10)
 
Mice homozygous for a knock-out allele exhibit increased body weight. Mice heterozygous for a maternally inherited knock-out allele exhibit increased placenta and body weight. Mice heterozygous for a different knock-out allele paternally inherited exhibit decreased fetal and postnatal body weight.
 
Mutations Annotated to Human Diseases (1)   
Gene Ontology
(GO)
classifications
All GO classifications: (4 annotations)
Process negative regulation of cell proliferation, regulation of gene expression
Component cytoplasm
External Resources: FuncBase
Expression
Literature Summary: (116 records)
Data Summary: Results (413)    Tissues (119)    Images (44)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 92
Northern blot 120
RT-PCR 155
RNase protection 46
cDNA source data(33)
Other mouse links: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(111) Genomic(47) cDNA(39) Primer pair(24) Other(1)
Microarray probesets(3)
Other database
links
VEGA Gene Model OTTMUSG00000014998 (Evidence)
Ensembl Gene Model ENSMUSG00000000031 (Evidence)
Entrez Gene 14955 (Evidence)
DFCI TC1573375, TC1644358, TC1655123, TC1708808
DoTS DT.101405939, DT.40137027, DT.91281068, DT.94224131
NIA Mouse Gene Index U029485
International Mouse Phenotyping Consortium Status H19
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000014998 VEGA Gene Model | MGI Sequence Detail 2615 C57BL/6J ±  kb
transcript NR_130973 RefSeq | MGI Sequence Detail 2288 C57BL/6 
polypeptide Q61639 UniProt | EBI | MGI Sequence Detail 147 Not Applicable 

For the selected sequences
All sequences(49) RefSeq(3) UniProt(2)
Polymorphisms
All PCR and RFLP(19) : PCR(3) RFLP(16) SNPs within 2kb(13 from dbSNP Build 137)
References
(Earliest) J:20185 Crouse HV, The controlling element in sex chromosome behavior in Sciara. Genetics. 1960;45:1425-43
(Latest) J:219210 Nikolaou KC, et al., Spontaneous development of hepatocellular carcinoma with cancer stem cell properties in PR-SET7-deficient livers. EMBO J. 2015 Feb 12;34(4):430-47
All references(280)
Other
accession IDs
MGD-MRK-10486, MGI:2142026

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
06/23/2015
MGI 5.22
The Jackson Laboratory