H19
Gene Detail

Symbol Name ID

H19 H19 fetal liver mRNA MGI:95891

Feature Type

lincRNA gene

Genetic Map

Chromosome 7

87.97 cM
Detailed Genetic Map ± 1 cM


Mapping data(40)

Sequence Map

Chr7:142575529-142578143 bp, - strand From VEGA annotation of GRCm38   2615 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

Gene Tree: H19

Alleles and phenotypes

All alleles(29) : Targeted(29)
 

Mice homozygous for a knock-out allele exhibit increased body weight. Mice heterozygous for a maternally inherited knock-out allele exhibit increased placenta and body weight. Mice heterozygous for a different knock-out allele paternally inherited exhibit decreased fetal and postnatal body weight.

 
Alleles Annotated to Human Diseases(1)   

Gene Ontology (GO) classifications

All GO classifications: (4 annotations)

Process	negative regulation of cell proliferation, regulation of gene expression
Component	cytoplasm

External Resources: FuncBase

Expression

Literature Summary: (108 records)
Data Summary: Results (411)    Tissues (113)    Images (42)
Theiler Stages: 4, 8, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 28

Assay Type	Results
RNA in situ	89
Northern blot	120
RT-PCR	156
RNase protection	46

cDNA source data(31)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(109) Genomic(47) cDNA(37) Primer pair(24) Other(1)
Microarray probesets(3)

Other database links

VEGA Gene Model	OTTMUSG00000014998 (Evidence)
Ensembl Gene Model	ENSMUSG00000000031 (Evidence)
Entrez Gene	14955 (Evidence)
DFCI	TC1573375, TC1644358
DoTS	DT.101405939, DT.40137027, DT.91281068, DT.94224131
NIA Mouse Gene Index	U029485
International Mouse Knockout Project Status	H19

Sequences

Length	Strain/Species
genomic	OTTMUSG00000014998	VEGA Gene Model | MGI Sequence Detail	2615	C57BL/6J
transcript	OTTMUST00000035613	VEGA | MGI Sequence Detail	2286	Not Applicable
polypeptide	Q61639	UniProt | EBI | MGI Sequence Detail	147	Not Applicable

All sequences(42) RefSeq(1) UniProt(2)

Polymorphisms

All PCR and RFLP(19) : PCR(3) RFLP(16) SNPs(0 from dbSNP Build 128)

References

(Earliest) J:20185 Crouse HV, The controlling element in sex chromosome behavior in Sciara. Genetics. 1960;45:1425-43
(Latest) J:194471 Borensztein M, et al., Myod and H19-Igf2 locus interactions are required for diaphragm formation in the mouse. Development. 2013 Mar;140(6):1231-9
All references(275)

Other accession IDs

MGD-MRK-10486, MGI:2142026