About   Help   FAQ
H13
Gene Detail
 Symbol
Name
ID
H13
histocompatibility 13
MGI:95886
Synonyms 1200006O09Rik, 4930443L17Rik, 5031424B04Rik, H-13, Spp
Feature Type protein coding gene
Genetic Map
Chromosome 2
75.41 cM
Detailed Genetic Map ± 1 cM


Mapping data(10)
Sequence Map
Chr2:152669461-152708670 bp, + strand
From VEGA annotation of GRCm38

  39210 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:7749  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Gene Tree: H13

Human
homologs
Human Homolog HM13, histocompatibility (minor) 13
NCBI Gene ID 81502
neXtProt AC  NX_Q8TCT9
Human Synonyms  dJ324O17.1, H13, IMP1, IMPAS, IMPAS-1, MSTP086, PSENL3, PSL3, SPP, SPPL1
Human Chr (Location)  20q11.21; chr20:31514410-31569569 (+)  GRCh38
Alleles
and
phenotypes
All alleles(27) : Gene trapped(26) Targeted(1)
Incidental mutations (data from Mutagenetix , APF )
 
This is one of several loci identified by development of congenic strains differing in resistance to transplantable tumors. C57BL/10 carries the a allele and B10.129(14M) carries the b allele.
 
Gene Ontology
(GO)
classifications
All GO classifications: (18 annotations)
Process membrane protein proteolysis, proteolysis
Component cell surface, endoplasmic reticulum, ...
Function aspartic endopeptidase activity, intramembrane cleaving, aspartic-type endopeptidase activity, ...
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (54)    Tissues (18)   
Theiler Stages: 10, 18, 23, 25, 28
Assay TypeResults
RNA in situ 28
RT-PCR 26
cDNA source data(177)
External Resources: Allen Institute   GEO   ArrayExpress
Molecular
reagents
All nucleic(182) cDNA(178) Primer pair(4)
Microarray probesets(10)
Other database
links
VEGA Gene ModelOTTMUSG00000015824 (Evidence)
Ensembl Gene ModelENSMUSG00000019188 (Evidence)
Entrez Gene14950 (Evidence)
UniGene277327
DFCITC1573047, TC1584248, TC1587865, TC1588110, TC1589010, TC1697481
DoTSDT.101710625, DT.495217, DT.55263571, DT.55275604, DT.94178805, DT.94359034, DT.97401570, DT.97401571
NIA Mouse Gene IndexU002650
EC3.4.23.-
PDB1INQ, 1JUF
Consensus CDS ProjectCCDS16896.1, CCDS50752.1, CCDS50753.1
International Mouse Knockout Project StatusH13
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000015824 VEGA Gene Model | MGI Sequence Detail 39210 C57BL/6J ±  kb
transcript OTTMUST00000037623 VEGA | MGI Sequence Detail 1743 Not Applicable 
polypeptide OTTMUSP00000016863 VEGA | MGI Sequence Detail 394 Not Applicable 

For the selected sequences
All sequences(93) RefSeq(11) UniProt(5)
Polymorphisms RFLP(1) : SNPs within 2kb(336 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR007369 Peptidase A22B, signal peptide peptidase
InterPro IPR006639 Peptidase A22, presenilin signal peptide
Protein Ontology PR:000008621 minor histocompatibility antigen H13
References (Earliest) J:5026 Graff RJ, et al., Histocompatibility genes of mice. VI. Allografts in mice congenic at various non-H-2 histocompatibility loci. Transplantation. 1966 Jul;4(4):425-37
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(53)
Other
accession IDs
MGD-MRK-10359, MGD-MRK-10481, MGI:1914866, MGI:1915400, MGI:2139237, MGI:2447815

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
07/15/2014
MGI 5.18
The Jackson Laboratory