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H13
Gene Detail
Symbol

Name
ID
H13
histocompatibility 13
MGI:95886
Synonyms
1200006O09Rik, 4930443L17Rik, 5031424B04Rik, H-13, Spp
Feature Type
protein coding gene
Genetic Map
Chromosome 2
75.41 cM
Detailed Genetic Map ± 1 cM


Mapping data(10)
Sequence Map
Chr2:152669461-152708670 bp, + strand
From VEGA annotation of GRCm38

  39210 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:7749  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

HCOP human homology predictions: HM13
Gene Tree: H13

Human
homologs
HM13, histocompatibility (minor) 13
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 81502
neXtProt AC: NX_Q8TCT9

Human Synonyms: dJ324O17.1, H13, IMP1, IMPAS, IMPAS-1, MSTP086, PSENL3, PSL3, SPP, SPPL1

Human Chr (Location): 20q11.21; chr20:31514410-31569567 (+)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(28) : Gene trapped(26) Targeted(2)
Incidental mutations (data from Mutagenetix , APF , CvDC )
 
This is one of several loci identified by development of congenic strains differing in resistance to transplantable tumors. C57BL/10 carries the a allele and B10.129(14M) carries the b allele.
 
Interactions
H13 interacts with 326 markers (Mir9-1, Mir9-2, Mir9-3, ...)
Expression
Literature Summary: (2 records)
Data Summary: Results (54)    Tissues (18)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 28
RT-PCR 26
cDNA source data(177)
Other mouse links: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(182) cDNA(178) Primer pair(4)
Microarray probesets(10)
Other database
links
VEGA Gene Model OTTMUSG00000015824 (Evidence)
Ensembl Gene Model ENSMUSG00000019188 (Evidence)
Entrez Gene 14950 (Evidence)
UniGene 277327
DFCI TC1573047, TC1584248, TC1587865, TC1588110, TC1589010, TC1697481
DoTS DT.101710625, DT.495217, DT.55263571, DT.55275604, DT.94178805, DT.94359034, DT.97401570, DT.97401571
NIA Mouse Gene Index U002650
EC 3.4.23.-
PDB 1INQ, 1JUF
Consensus CDS Project CCDS16896.1, CCDS50752.1, CCDS50753.1
International Mouse Phenotyping Consortium Status H13
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000015824 VEGA Gene Model | MGI Sequence Detail 39210 C57BL/6J ±  kb
transcript OTTMUST00000037623 VEGA | MGI Sequence Detail 1743 Not Applicable 
polypeptide OTTMUSP00000016863 VEGA | MGI Sequence Detail 394 Not Applicable 

For the selected sequences
All sequences(96) RefSeq(13) UniProt(5)
Polymorphisms
RFLP(1) : SNPs within 2kb(336 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR007369 Peptidase A22B, signal peptide peptidase
InterPro IPR006639 Peptidase A22, presenilin signal peptide
Protein Ontology PR:000008621 minor histocompatibility antigen H13
References
(Earliest) J:5026 Graff RJ, et al., Histocompatibility genes of mice. VI. Allografts in mice congenic at various non-H-2 histocompatibility loci. Transplantation. 1966 Jul;4(4):425-37
(Latest) J:206256 Oliveira CC, et al., New role of signal peptide peptidase to liberate C-terminal peptides for MHC class I presentation. J Immunol. 2013 Oct 15;191(8):4020-8
All references(54)
Other
accession IDs
MGD-MRK-10359, MGD-MRK-10481, MGI:1914866, MGI:1915400, MGI:2139237, MGI:2447815

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/21/2015
MGI 5.22
The Jackson Laboratory