H1 Gene Detail

Summary

• Symbol
  H1
• Name
  histocompatibility 1
• Synonyms
  H-1

• Feature Type
  protein coding gene
• IDs
  MGI:95882
  NCBI Gene: 109740
• Alliance
  gene page

Location &
Maps

• Sequence Map
  Genome coordinates not available from the current reference assembly.

• Genetic Map
  Chromosome 7, Syntenic
• Mapping Data
  12 experiments

Mutations,
Alleles, and
Phenotypes

This gene was discovered by differences in strain resistance to transplantable tumors. The a and b alleles are found in congenic strains C3H and C3H.K, respectively. At least 6 alleles are known. Antigen is present on many tissues, including transplantable tumors, skin, thymocytes and macrophages.

Sequences &
Gene Models

• NCBI Gene
  109740

Other
Accession IDs

MGD-MRK-10355, MGD-MRK-10477

References

• Summaries
  All 18
• Earliest
  J:117 SNELL GD, et al., Histocompatibility genes of the mouse. II. Production and analysis of isogenic resistant lines. J Natl Cancer Inst. 1958 Nov;21(5):843-77
• Latest
  J:10517 Fast LD, Identification of a single non-H-2 gene regulating graft-versus-host disease response. J Immunol. 1990 Jun 1;144(11):4177-82