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Galt
Gene Detail
 Symbol
Name
ID
Galt
galactose-1-phosphate uridyl transferase
MGI:95638
Feature Type protein coding gene
Genetic Map
Chromosome 4
22.07 cM
Detailed Genetic Map ± 1 cM


Mapping data(10)
Sequence Map
Chr4:41755228-41758695 bp, + strand
From VEGA annotation of GRCm38

  3468 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:126  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Protein SuperFamily: galactose-1-phosphate uridylyltransferase
Gene Tree: Galt

Human
homologs
Human Homolog GALT, galactose-1-phosphate uridylyltransferase
NCBI Gene ID 2592
neXtProt AC  NX_P07902
Human Chr (Location)  9p13; chr9:34646589-34650598 (+)  GRCh38
Disease Associations  (1) Diseases Associated with Human GALT
Mutations,
alleles, and
phenotypes
All mutations/alleles(2) : Targeted(2)
Incidental mutations (data from APF )
 
Homozygotes for a targeted null mutation exhibit abnormal galactose metabolism, but lack symptoms of acute toxicity seen in humans with galactosemia.
 
Interactions
Galt interacts with 68 markers (Mir18, Mir19b-1, Mir19b-2, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (12 annotations)
Process carbohydrate metabolic process, galactose metabolic process, ...
Component Golgi apparatus
Function catalytic activity, metal ion binding, ...
External Resources: FuncBase
Expression
Literature Summary: (3 records)
Data Summary: Results (121)    Tissues (112)    Images (4)
Theiler Stages: 11, 13, 22, 23
Assay TypeResults
RNA in situ 121
cDNA source data(58)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(63) Genomic(3) cDNA(59) Other(1)
Microarray probesets(4)
Other database
links
VEGA Gene ModelOTTMUSG00000006678 (Evidence)
Ensembl Gene ModelENSMUSG00000036073 (Evidence)
Entrez Gene14430 (Evidence)
UniGene439669
DFCITC1579669, TC1596376, TC1630028
DoTSDT.101301916, DT.91446979, DT.94336811, DT.97380344
NIA Mouse Gene IndexU004218
EC2.7.7.12
Consensus CDS ProjectCCDS38720.1
International Mouse Knockout Project StatusGalt
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000006678 VEGA Gene Model | MGI Sequence Detail 3468 C57BL/6J ±  kb
transcript OTTMUST00000015297 VEGA | MGI Sequence Detail 1595 Not Applicable 
polypeptide OTTMUSP00000007068 VEGA | MGI Sequence Detail 360 Not Applicable 

For the selected sequences
All sequences(53) RefSeq(4) UniProt(4)
Polymorphisms RFLP(1) : SNPs within 2kb(80 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR001937 Galactose-1-phosphate uridyl transferase, class I
InterPro IPR019779 Galactose-1-phosphate uridyl transferase, class I His-active site
InterPro IPR005850 Galactose-1-phosphate uridyl transferase, C-terminal
InterPro IPR005849 Galactose-1-phosphate uridyl transferase, N-terminal
InterPro IPR011146 HIT-like domain
Protein Ontology PR:000007834 galactose-1-phosphate uridylyltransferase
References (Earliest) J:6674 Stallings RL, et al., Confirmational, provisional, and/or regional assignment of 15 enzyme loci onto Chinese hamster autosomes 1, 2, and 7. Somatic Cell Genet. 1981 Nov;7(6):683-98
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(46)
Other
accession IDs
MGD-MRK-9964, MGI:2147374

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/19/2014
MGI 5.19
The Jackson Laboratory