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Dnajc5
Gene Detail
Symbol

Name
ID
Dnajc5
DnaJ (Hsp40) homolog, subfamily C, member 5
MGI:892995
Synonyms
2610314I24Rik, Csp
Feature Type
protein coding gene
Genetic Map
Chromosome 2
103.63 cM
Detailed Genetic Map ± 1 cM


Mapping data(7)
Sequence Map
Chr2:181520485-181555133 bp, + strand
From VEGA annotation of GRCm38

  34649 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:9631  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 2 zebrafish

Protein SuperFamily: cysteine string protein
Gene Tree: Dnajc5

Human
homologs
Human Homolog DNAJC5, DnaJ (Hsp40) homolog, subfamily C, member 5
NCBI Gene ID 80331
neXtProt AC  NX_Q9H3Z4
Human Synonyms  CLN4, CLN4B, CSP, DNAJC5A, NCL
Human Chr (Location)  20q13.33; chr20:63895102-63936031 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(47) : Gene trapped(45) Targeted(2)
Incidental mutations (data from APF )
 
Mice homozygous for disruptions in this gene die within the first 3 months of live and abnormalities in their neuromuscular synapses. This results in various defects in movement and coordination.
 
Phenotype Images(2)
Interactions
Dnajc5 interacts with 460 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (2 records)
Data Summary: Results (1)    Tissues (1)    Images (1)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 1
cDNA source data(14)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(17) cDNA(16) Other(1)
Microarray probesets(10)
Other database
links
VEGA Gene ModelOTTMUSG00000016739 (Evidence)
Ensembl Gene ModelENSMUSG00000000826 (Evidence)
Entrez Gene13002 (Evidence)
DFCITC1577904, TC1601668, TC1719080, TC1608598, TC1601850
DoTSDT.101399117, DT.101282068, DT.110731710, DT.101399124, DT.101399118, DT.534204
NIA Mouse Gene IndexU002987
PDB2CTW
Consensus CDS ProjectCCDS17215.1
International Mouse Knockout Project StatusDnajc5
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000016739 VEGA Gene Model | MGI Sequence Detail 34649 C57BL/6J ±  kb
transcript OTTMUST00000040585 VEGA | MGI Sequence Detail 6578 Not Applicable 
polypeptide OTTMUSP00000018139 VEGA | MGI Sequence Detail 198 Not Applicable 

For the selected sequences
All sequences(81) RefSeq(7) UniProt(9)
Polymorphisms
RFLP(2) : SNPs within 2kb(143 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR001623 DnaJ domain
InterPro IPR018253 DnaJ domain, conserved site
Protein Ontology PR:000006588 DnaJ homolog subfamily C member 5
References
(Earliest) J:37096 Chin H, et al., Genetic mapping of the gene encoding cysteine string protein. Mamm Genome. 1997 Jun;8(6):456-7
(Latest) J:202023 Ruiz R, et al., alpha-Synuclein A30P decreases neurodegeneration and increases synaptic vesicle release probability in CSPalpha-null mice. Neuropharmacology. 2014 Jan;76 Pt A:106-17
All references(58)
Other
accession IDs
MGI:1919766, MGI:2139168

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
12/09/2014
MGI 5.20
The Jackson Laboratory