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Serpina1c
Gene Detail
Symbol

Name
ID
Serpina1c
serine (or cysteine) peptidase inhibitor, clade A, member 1C
MGI:891969
Synonyms
PI3, PI6, Spi1-3, Spi1-6
Feature Type
protein coding gene
Genetic Map
Chromosome 12
52.98 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr12:103894926-103904887 bp, - strand
From VEGA annotation of GRCm38

  9962 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:20103  Vertebrate Homology Class
1 human; 5 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 4 chicken; 3 western clawed frog; 2 zebrafish

Protein SuperFamily: serpin
Gene Tree: Serpina1c

Human
homologs
Human Homolog SERPINA1, serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
NCBI Gene ID 5265
neXtProt AC  NX_P01009
Human Synonyms  A1A, A1AT, AAT, alpha1AT, PI, PI1, PRO2275
Human Chr (Location)  14q32.1; chr14:94376747-94390692 (-)  GRCh38
Disease Associations  (2) Diseases Associated with Human SERPINA1
Mutations,
alleles, and
phenotypes
Incidental mutations (data from Mutagenetix , APF )
Interactions
Serpina1c interacts with 14 markers (Mir22, Mir155, Mir218-2, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (2 records)
Data Summary: Results (97)    Tissues (47)    Images (24)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 97
cDNA source data(11)
External Resources: GEO   Expression Atlas
Molecular
reagents
All nucleic(12) Genomic(1) cDNA(11)
Microarray probesets(4)
Other database
links
VEGA Gene ModelOTTMUSG00000023935 (Evidence)
Ensembl Gene ModelENSMUSG00000079015 (Evidence)
Entrez Gene20702 (Evidence)
Consensus CDS ProjectCCDS26141.1
International Mouse Knockout Project StatusSerpina1c
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000023935 VEGA Gene Model | MGI Sequence Detail 9962 C57BL/6J ±  kb
transcript OTTMUST00000058482 VEGA | MGI Sequence Detail 1361 Not Applicable 
polypeptide OTTMUSP00000028336 VEGA | MGI Sequence Detail 413 Not Applicable 

For the selected sequences
All sequences(21) RefSeq(2) UniProt(1)
Polymorphisms
RFLP(3) : SNPs within 2kb(253 from dbSNP Build 137)    SNPs within 2kb including multiple locations(411)
Protein-related
information
ResourceIDDescription
InterPro IPR023795 Protease inhibitor I4, serpin, conserved site
InterPro IPR023796 Serpin domain
InterPro IPR000215 Serpin family
Protein Ontology PR:000015929 alpha-1-antitrypsin 1-3
References
(Earliest) J:19360 Hill RE, et al., Plasma protease inhibitors in mouse and man: divergence within the reactive centre regions. Nature. 1984 Sep 13-19;311(5982):175-7
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(28)
Other
accession IDs
MGI:891966

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
11/18/2014
MGI 5.20
The Jackson Laboratory