Cyp2a4
Gene Detail

Symbol Name ID

Cyp2a4 cytochrome P450, family 2, subfamily a, polypeptide 4 MGI:88596

Synonyms

Cyp15a1, D7Ucla4, testosterone 15alpha-hydroxylase

Feature Type

protein coding gene

Genetic Map

Chromosome 7

14.39 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)

Sequence Map

Chr7:26307192-26315088 bp, + strand From NCBI annotation of GRCm38   7897 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:85917  Vertebrate Homology Class
1 human; 2 mouse; 1 rat; 2 rhesus macaque; 1 cattle; 1 dog

Protein SuperFamily: cytochrome P450 CYP2D6
Gene Tree: Cyp2a4

Human homologs

Human Homolog		CYP2A13, cytochrome P450, family 2, subfamily A, polypeptide 13
NCBI Gene ID		1553
neXtProt AC		NX_Q16696
Human Synonyms		CPAD, CYP2A, CYPIIA13
Human Chr (Location)		19q13.2; chr19:41594356-41602100 (+)  GRCh37.p10

Gene Ontology (GO) classifications

All GO classifications: (1 annotations)

Function

heme binding

External Resources: FuncBase

Expression

Literature Summary: (3 records)
Data Summary: Results (113)    Tissues (107)    Images (8)
Theiler Stages: 10, 18, 22, 23, 25, 28

Assay Type	Results
RNA in situ	101
RT-PCR	12

cDNA source data(9)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(15) Genomic(4) cDNA(10) Primer pair(1)
Microarray probesets(2)

Other database links

Ensembl Gene Model	ENSMUSG00000074254 (Evidence)
Entrez Gene	13086 (Evidence)
Consensus CDS Project	CCDS21002.1
International Mouse Knockout Project Status	Cyp2a4

Sequences

Length	Strain/Species
genomic	13086	NCBI Gene Model | MGI Sequence Detail	7897	C57BL/6J
transcript	NM_009997	RefSeq | MGI Sequence Detail	1715	FVB/N
polypeptide	NP_034127	RefSeq | MGI Sequence Detail	494	FVB/N

All sequences(21) RefSeq(2)

Polymorphisms

RFLP(2) : SNPs(91 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
Protein Ontology	PR:000006220	cytochrome P450 2A4

References

(Earliest) J:30977 Burkhart BA, et al., Sexual dimorphism of testosterone 15 alpha-hydroxylase mRNA levels in mouse liver. cDNA cloning and regulation. J Biol Chem. 1985 Dec 5;260(28):15357-61
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(31)

Other accession IDs

MGD-MRK-18618, MGD-MRK-2298, MGD-MRK-2313, MGI:101806, MGI:2142076