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Cryz Gene Detail
Summary
  • Symbol
    Cryz
  • Name
    crystallin, zeta
  • Synonyms
    quinone reductase, Sez9, SEZ9
  • Feature Type
    protein coding gene
  • IDs
    MGI:88527
    NCBI Gene: 12972
  • Gene Overview
    MyGene.info: CRYZ
Location & Maps
more
  • Sequence Map
    Chr3:154596711-154623182 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      26472 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 3, 79.25 cM
  • Mapping Data
    3 experiments
Homology
more
  • Human Ortholog
    CRYZ, crystallin zeta
  • Vertebrate Orthologs
    10
  • Human Ortholog
    CRYZ, crystallin zeta
    Orthology source: HomoloGene, HGNC
  • Links
    NCBI Gene ID: 1429
    neXtProt AC: NX_Q08257

  • Chr Location
    1p31.1; chr1:74705482-74733408 (-)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    6 phenotype references
  • All Mutations and Alleles
    9
  • Gene trapped
    3
  • Targeted
    6
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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  • cDNA Data
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000022729 VEGA Gene Model | MGI Sequence Detail 26472 C57BL/6J ±  kb
transcript OTTMUST00000054516 VEGA | MGI Sequence Detail 2507 Not Applicable  
polypeptide OTTMUSP00000026037 VEGA | MGI Sequence Detail 331 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    129 from dbSNP Build 142
Protein
Information
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  • UniProt
    11 Sequences
  • EC
  • InterPro Domains
    IPR013149 Alcohol dehydrogenase, C-terminal
    IPR013154 Alcohol dehydrogenase, N-terminal
    IPR002085 Alcohol dehydrogenase superfamily, zinc-type
    IPR011032 GroES-like
    IPR016040 NAD(P)-binding domain
    IPR020843 Polyketide synthase, enoylreductase domain
    IPR002364 Quinone oxidoreductase/zeta-crystallin, conserved site
Molecular
Reagents
less
  • All nucleic 114
    Genomic 3
    cDNA 111

    Microarray probesets 4
Other
Accession IDs
less
MGD-MRK-2182
References
more
  • Summaries
    All 34
    Gene Ontology 5
    Phenotypes 6
  • Earliest
    J:20118 Wistow G, et al., Recruitment of enzymes as lens structural proteins. Science. 1987 Jun 19;236(4808):1554-6
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/27/2016
MGI 6.05
The Jackson Laboratory