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Cryz Gene Detail
Summary
  • Symbol
    Cryz
  • Name
    crystallin, zeta
  • Synonyms
    quinone reductase, Sez9, SEZ9
  • Feature Type
    protein coding gene
  • IDs
    MGI:88527
    NCBI Gene: 12972
  • Gene Overview
    MyGene.info: CRYZ
  • Alliance
  • Transcription Start Sites
    7 TSS
Location &
Maps
more
  • Sequence Map
    Chr3:154596711-154623182 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 3, 79.25 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    129 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_88527
protein coding gene Chr3:154596711-154623182 (.)
129S1/SvImJ MGP_129S1SvImJ_G0028004
protein coding gene Chr3:158613232-158643043 (+)
A/J MGP_AJ_G0027963
protein coding gene Chr3:152823101-152850225 (+)
AKR/J MGP_AKRJ_G0027929
protein coding gene Chr3:156911396-156939710 (+)
BALB/cJ MGP_BALBcJ_G0027975
protein coding gene Chr3:152628873-152658751 (+)
C3H/HeJ MGP_C3HHeJ_G0027705
protein coding gene Chr3:157285040-157311244 (+)
C57BL/6NJ MGP_C57BL6NJ_G0028418
protein coding gene Chr3:163791295-163816497 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0025756
protein coding gene Chr3:147584381-147608997 (+)
CAST/EiJ MGP_CASTEiJ_G0027158
protein coding gene Chr3:157411998-157438852 (+)
CBA/J MGP_CBAJ_G0027680
protein coding gene Chr3:169682114-169708267 (+)
DBA/2J MGP_DBA2J_G0027820
protein coding gene Chr3:151894639-151920432 (+)
FVB/NJ MGP_FVBNJ_G0027787
protein coding gene Chr3:149269702-149294032 (+)
LP/J MGP_LPJ_G0027931
protein coding gene Chr3:159934108-159960837 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0027820
protein coding gene Chr3:178119879-178145551 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0028477
protein coding gene Chr3:156556767-156582218 (+)
PWK/PhJ MGP_PWKPhJ_G0026881
protein coding gene Chr3:151825932-151854168 (+)
SPRET/EiJ MGP_SPRETEiJ_G0026709
protein coding gene Chr3:154718887-154745269 (+)
WSB/EiJ MGP_WSBEiJ_G0027238
protein coding gene Chr3:157544956-157569820 (+)



Homology
more
  • Human Ortholog
    CRYZ, crystallin zeta
  • Vertebrate Orthologs
    10
  • Human Ortholog
    CRYZ, crystallin zeta
    Orthology source: HGNC, HomoloGene
  • Links
    NCBI Gene ID: 1429
    neXtProt AC: NX_Q08257
    UniProt: Q08257

  • Chr Location
    1p31.1; chr1:74705482-74733408 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 12972 NCBI Gene Model | MGI Sequence Detail 26472 C57BL/6J ±  kb
transcript NM_009968 RefSeq | MGI Sequence Detail 2519 C57BL/6  
polypeptide P47199 UniProt | EBI | MGI Sequence Detail 331 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 115
    Genomic 3
    cDNA 112

    Microarray probesets 4
Other
Accession IDs
less
MGD-MRK-2182
References
more
  • Summaries
    All 38
    Gene Ontology 7
    Phenotypes 6
  • Earliest
    J:20118 Wistow G, et al., Recruitment of enzymes as lens structural proteins. Science. 1987 Jun 19;236(4808):1554-6
  • Latest
    J:265628 Gaudet P, et al., Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief Bioinform. 2011 Sep;12(5):449-62

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/27/2018
MGI 6.13
The Jackson Laboratory