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cl Gene Detail
Summary
  • Symbol
    cl
  • Name
    clubfoot
  • Feature Type
    heritable phenotypic marker
  • IDs
    MGI:88415
Location & Maps
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  • Sequence Map
    Genome coordinates not available
  • Genetic Map
    Chromosome Unknown
Human Diseases
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  • Diseases
    1 with cl mouse models

Human Disease Mouse Models
       Clubfoot, Congenital, with or without Deficiency of Long Bones and/or Mirror-Image Polydactyly; CCF   OMIM: 119800 View 1 model
Click on a disease name to see all genes associated with that disease.

  • Mutations/Alleles
    1 with disease annotations
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    22 phenotypes from 1 allele in 1 genetic background
    1 phenotype reference
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    1
  • Spontaneous
    1
Homozygous mutation of this gene results in reduced viability, reduced growth, and clubbed hindfeet. 59% of mutants die before 14 days of age. Some carpal and tarsal fusion is observed. Mutants have a gummy discharge on the eyes. One or both forefeet mayalso show abnormalities.
Other
Accession IDs
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MGD-MRK-2005
References
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  • Summaries
    All 1
    Diseases 1
    Phenotypes 1
  • Earliest
    J:294 Robins MW, A mutation causing congenital clubfoot in the house mouse. J Hered. 1959;50:188-192

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
06/22/2016
MGI 6.04
The Jackson Laboratory