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cl
Gene Detail
Symbol

Name
ID
cl
clubfoot
MGI:88415
Feature Type
heritable phenotypic marker
Genetic Map
Chromosome Unknown
Mutations,
alleles, and
phenotypes
All mutations/alleles(1) : Spontaneous(1)
 
Homozygous mutation of this gene results in reduced viability, reduced growth, and clubbed hindfeet. 59% of mutants die before 14 days of age. Some carpal and tarsal fusion is observed. Mutants have a gummy discharge on the eyes. One or both forefeet may also show abnormalities.
 
Human Diseases Modeled Using Mouse cl (1)    Alleles Annotated to Human Diseases(1)   
References
(Earliest) J:294 Robins MW, A mutation causing congenital clubfoot in the house mouse. J Hered. 1959;50:188-192
All references(1)
Disease annotation references (1)
Other
accession IDs
MGD-MRK-2005

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
11/18/2014
MGI 5.20
The Jackson Laboratory