cl
Gene Detail

Symbol Name ID

cl clubfoot MGI:88415

Feature Type

heritable phenotypic marker

Genetic Map

Chromosome Unknown

Alleles and phenotypes

All alleles(1) : Spontaneous(1)
 

Homozygous mutation of this gene results in reduced viability, reduced growth, and clubbed hindfeet. 59% of mutants die before 14 days of age. Some carpal and tarsal fusion is observed. Mutants have a gummy discharge on the eyes. One or both forefeet may also show abnormalities.

 
Human Diseases Modeled Using Mouse cl (1)    Alleles Annotated to Human Diseases(1)   

References

(Earliest) J:294 Robins MW, A mutation causing congenital clubfoot in the house mouse. J Hered. 1959;50:188-192
All references(1)

Other accession IDs

MGD-MRK-2005