ckr
Gene Detail

Symbol Name ID

ckr chakragati MGI:88414

Feature Type

heritable phenotypic marker

Genetic Map

Chromosome 16
Syntenic

Mapping data(2)

Alleles and phenotypes

All alleles(1) : Transgenic(1)
 

Animals homozygous for this mutation exhibit circling behavior almost continuously throughout the night. During daytime, circling behavior is observed in response to stress.

 
Human Diseases Modeled Using Mouse ckr (1)    Alleles Annotated to Human Diseases(1)   

Gene Ontology (GO) classifications

All GO classifications: (2 annotations)

Process

locomotory behavior, negative regulation of dopamine receptor signaling pathway

External Resources: FuncBase

Molecular reagents

All nucleic(1) Genomic(1)

Other database links

Entrez Gene

12717

Polymorphisms

RFLP(1) : SNPs(0 from dbSNP Build 128)

References

(Earliest) J:10932 Ratty AK, et al., Circling behavior exhibited by a transgenic insertional mutant. Brain Res Mol Brain Res. 1990 Oct;8(4):355-8
(Latest) J:169719 Dawe GS, et al., Antipsychotic drugs dose-dependently suppress the spontaneous hyperactivity of the chakragati mouse. Neuroscience. 2010 Nov 24;171(1):162-72
All references(13)

Other accession IDs

MGD-MRK-2004