Homozygotes for targeted mutations may exhibit reduced body size and viability, impaired retinal development, pregnancy-insensitive mammary glands, and modified development of mammary cancer induced by neu and ras oncogenes, depending on the specific allele or genetic background.
|Process||canonical Wnt signaling pathway, cell cycle, ...|
|Component||bicellular tight junction, cyclin-dependent protein kinase holoenzyme complex, ...|
|Function||cyclin-dependent protein serine/threonine kinase regulator activity, enzyme binding, ...|
|RNA in situ||464|
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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