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Apo Gene Detail
Summary
  • Symbol
    Apo
  • Name
    anterior polar opacity
  • Feature Type
    heritable phenotypic marker
  • IDs
    MGI:88048
    NCBI Gene: 104237
  • Alliance
Location & Maps
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  • Sequence Map
    Genome coordinates not available
  • Genetic Map
    Chromosome Unknown
Human Diseases
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  • Diseases
    1 with Apo mouse models

Human Disease Mouse Models
      
IDs
View 1 model
Click on a disease name to see all genes associated with that disease.

  • Mutations/Alleles
    1 with disease annotations
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    10 phenotypes from 1 allele in 1 genetic background
    3 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Homozygous mutation of this gene is embryonic lethal. Heterozygous mutants are hyperactive, display circling behavior, cataracts, and some degree of reduced viability as the frequency of heterozygotes is less than the expected Mendelian ratio.
Sequences &
Gene Models
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Other
Accession IDs
less
MGD-MRK-1363
References
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  • Summaries
    All 5
    Diseases 1
    Phenotypes 3
  • Earliest
    J:6686 Kratochvilova J, Dominant cataract mutations detected in offspring of gamma-irradiated male mice. J Hered. 1981 Sep-Oct;72(5):302-7
  • Latest
    J:9528 Kratochvilova J, et al., Phenotypic characterization and genetic analysis of twenty dominant cataract mutations detected in offspring of irradiated male mice. Genet Res. 1988 Oct;52(2):125-34

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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Funding Information
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last database update
11/14/2017
MGI 6.11
The Jackson Laboratory