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Cat4
Gene Detail
 Symbol
Name
ID
Cat4
dominant cataract 4
MGI:88040
Synonyms anterior pyramidal cataract, Apc-1, Apcat1, Apcat-1, Apyc, Pcs-2, polar cataract and small eye 2
Feature Type heritable phenotypic marker
Genetic Map
Chromosome 8
Syntenic

Mapping data(1)
Alleles
and
phenotypes
All alleles(3) : Spontaneous(1) Radiation induced(2)
 
Homozygotes and heterozygous mutants display eye defects with some or all of: anterior lens opacity with polar adhesions, corneal opacity, anscoria, iris dysplasia, and microphthalmia. For some alleles, homozygotes show anophthalmia or embryonic lethality.
 
Gene Ontology
(GO)
classifications
All GO classifications: (1 annotations)
Process camera-type eye development
External Resources: FuncBase
Other database
links
Entrez Gene109738
References (Earliest) J:6686 Kratochvilova J, Dominant cataract mutations detected in offspring of gamma-irradiated male mice. J Hered. 1981 Sep-Oct;72(5):302-7
(Latest) J:49424 Grimes PA, et al., Abnormal eye development associated with Cat4a, a dominant mouse cataract mutation on chromosome 8. Invest Ophthalmol Vis Sci. 1998 Sep;39(10):1863-9
All references(7)
Other
accession IDs
MGD-MRK-1318, MGD-MRK-13189, MGD-MRK-1348, MGD-MRK-1349, MGD-MRK-1350, MGD-MRK-1383

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
04/08/2014
MGI 5.17
The Jackson Laboratory