Tg(KRT5-Cxcl13)F12Rlep
Transgene Detail

Summary

• Symbol: Tg(KRT5-Cxcl13)F12Rlep
• Name: transgene insertion F12, Rozen Le Panse
• MGI ID: MGI:6331227
• Synonyms: K5-CXCL13
• Transgene: Tg(KRT5-Cxcl13)F12Rlep Location: unknown
• Alliance: Tg(KRT5-Cxcl13)F12Rlep page

Transgene origin

• Strain of Origin: C57BL/6

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(KRT5-Cxcl13)F12Rlep expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Cxcl13 (MGI:1888499)

• Tg(KRT5-Cxcl13)F12Rlep expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  cattle	KRT5 (281268)

• A bovine K5 promoter drives expression of a mouse Cxcl3 cDNA. (J:277193)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:277193 Weiss JM, et al., Novel CXCL13 transgenic mouse: inflammation drives pathogenic effect of CXCL13 in experimental myasthenia gravis. Oncotarget. 2016 Feb 16;7(7):7550-62
• All: 1 reference(s)