Tg(SFTPC-Fstl1)2Ning
Transgene Detail

Summary

• Symbol: Tg(SFTPC-Fstl1)2Ning
• Name: transgene insertion 2, Wen Ning
• MGI ID: MGI:6188877
• Transgene: Tg(SFTPC-Fstl1)2Ning Location: unknown
• Alliance: Tg(SFTPC-Fstl1)2Ning page

Transgene origin

• Strain of Origin: Not Specified

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Mutation details: The human SFTPC promoter was used to drive the expression of mouse Fstl1 gene. Three lines were generated; the second line was back-crossed onto C57BL/6J background for at least 12 generations for further analysis. Increased expression was seen in lung epithelium as early as E12.5 and through adulthood. (J:249155)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:249155 Li X, et al., Apical Secretion of FSTL1 in the Respiratory Epithelium for Normal Lung Development. PLoS One. 2016;11(6):e0158385
• All: 1 reference(s)