Tg(Grm2-IL2RA/EGFP)1Nak
Transgene Detail

Summary

• Symbol: Tg(Grm2-IL2RA/EGFP)1Nak
• Name: transgene insertion 1, Shigetada Nakanishi
• MGI ID: MGI:6116470
• Synonyms: IG17, MG-IG, mGluR2-GFP, Tg(Grm2-IL2RA/EGFP)IG8Nak, Tg(Grm2-IL2RA/GFP)1Nak, TgN(grm2-IL2RA/GFP)1kyo
• Transgene: Tg(Grm2-IL2RA/EGFP)1Nak Location: unknown
• Alliance: Tg(Grm2-IL2RA/EGFP)1Nak page

Transgene origin

• Strain of Origin: (C57BL/6J x DBA/2J)F1

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence, Reporter)
• Mutation: Insertion
• Tg(Grm2-IL2RA/EGFP)1Nak expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  IL2RA (3559)

  Il2ra

  (MGI:96549)

  Expresses an IL2RA/GFP fusion protein.

• Tg(Grm2-IL2RA/EGFP)1Nak expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Grm2 (MGI:1351339)

• Mutation details: The mouse 18.3 kb 5-upstream genomic sequence containing the first and second exons of the Grm2 gene drives expression of a human IL-2Ralpha/EGFP gene fusion gene. Seven independent lines were generated (line numbers not specified). (J:131116)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:131116 Watanabe D, et al., Ablation of cerebellar Golgi cells disrupts synaptic integration involving GABA inhibition and NMDA receptor activation in motor coordination. Cell. 1998 Oct 2;95(1):17-27
• All: 10 reference(s)