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Tg(tetO-NRG1_i4)6Ajla
Transgene Detail
Summary
Symbol: Tg(tetO-NRG1_i4)6Ajla
Name: transgene insertion 6, Amanda J Law
MGI ID: MGI:5784536
Synonyms: NRGI-IV
Transgene: Tg(tetO-NRG1_i4)6Ajla  Location: unknown  
Alliance: Tg(tetO-NRG1_i4)6Ajla page
Transgene
origin
Strain of Origin:  C57BL/6J
Transgene
description
Transgene Type:    Transgenic (Humanized sequence, Inducible, Inserted expressed sequence)
Inducer:    doxycycline/tetracycline
Mutation:    Insertion
 
Tg(tetO-NRG1_i4)6Ajla expresses 1 gene
 
Mutation detailsThe tetracycline responsive promoter drives inducible expression of the human isoform IV cDNA. Two lines, 6 and 13 were described. Line 6 is entered as the representative line. (J:231737)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:231737 Papaleo F, et al., Behavioral, Neurophysiological, and Synaptic Impairment in a Transgenic Neuregulin1 (NRG1-IV) Murine Schizophrenia Model. J Neurosci. 2016 Apr 27;36(17):4859-75
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory