Tg(MMTV-DMTF1_i2)7Kai
Transgene Detail
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Symbol: |
Tg(MMTV-DMTF1_i2)7Kai |
Name: |
transgene insertion 7, Kazushi Inoue |
MGI ID: |
MGI:5698356 |
Synonyms: |
MMTV-DMP1beta, MMTV-DMP1betaV5His |
Transgene: |
Tg(MMTV-DMTF1_i2)7Kai Location: unknown
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Alliance: |
Tg(MMTV-DMTF1_i2)7Kai page
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Transgene Type: |
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Transgenic (Epitope tag, Humanized sequence, Inserted expressed sequence) |
Mutation: |
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Insertion
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Tg(MMTV-DMTF1_i2)7Kai expresses
1 gene
Transgene expresses:
Organism |
Expressed Gene |
Homolog in Mouse |
Note |
human |
DMTF1 (9988) |
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Transgene expresses isoform 2 known as beta. |
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Mutation details: The human DMTF1 beta (isoform 2) cDNA with V5 and 6x His tags is under the control of the MMTV-LTR promoter. Four lines were established: 7, 10, 13, and 22, founder line 7 is a representative line. The primary investigator indicates that phenotype is similar in all lines. Western blot and qRT-PCR analyses confirmed expression of protein and mRNA in the mammary glands.
(J:220608)
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Original: |
J:220608 Maglic D, et al., DMP1beta, a splice isoform of the tumour suppressor DMP1 locus, induces proliferation and progression of breast cancer. J Pathol. 2015 May;236(1):90-102 |
All: |
1 reference(s) |
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