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Tg(MMTV-DMTF1_i2)7Kai
Transgene Detail
Summary
Symbol: Tg(MMTV-DMTF1_i2)7Kai
Name: transgene insertion 7, Kazushi Inoue
MGI ID: MGI:5698356
Synonyms: MMTV-DMP1beta, MMTV-DMP1betaV5His
Transgene: Tg(MMTV-DMTF1_i2)7Kai  Location: unknown  
Alliance: Tg(MMTV-DMTF1_i2)7Kai page
Transgene
origin
Strain of Origin:  FVB/NJ
Transgene
description
Transgene Type:    Transgenic (Epitope tag, Humanized sequence, Inserted expressed sequence)
Mutation:    Insertion
 
Tg(MMTV-DMTF1_i2)7Kai expresses 1 gene
 
Mutation detailsThe human DMTF1 beta (isoform 2) cDNA with V5 and 6x His tags is under the control of the MMTV-LTR promoter. Four lines were established: 7, 10, 13, and 22, founder line 7 is a representative line. The primary investigator indicates that phenotype is similar in all lines. Western blot and qRT-PCR analyses confirmed expression of protein and mRNA in the mammary glands. (J:220608)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:220608 Maglic D, et al., DMP1beta, a splice isoform of the tumour suppressor DMP1 locus, induces proliferation and progression of breast cancer. J Pathol. 2015 May;236(1):90-102
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/12/2024
MGI 6.23
The Jackson Laboratory