Tg(S100b-EGFP)11Lgrv
Transgene Detail

Summary

• Symbol: Tg(S100b-EGFP)11Lgrv
• Name: transgene insertion 11, Catherine Legraverend
• MGI ID: MGI:5648257
• Transgene: Tg(S100b-EGFP)11Lgrv Location: unknown
• Alliance: Tg(S100b-EGFP)11Lgrv page

Transgene origin

• Strain of Origin: (C57BL/6N x DBA/2N)F1

Transgene description

• Transgene Type: Transgenic (Reporter)
• Mutation: Insertion
• Mutation details: The transgene expressed EGFP under the control of a 4.8 kb mouse S100B promoter gene sequence located 5' to the translation initiation site. Several transgenic lines were generated, with lines 4, 9, and 11 displayed identical EGFP expression patterns. Line 11 displays the highest level of EGFP expression and was expanded and studied further. In adult mice, the highest level of EGFP expression was found in ependymocytes; astrocytes; and spinal, medullar, pontine, and deep cerebellar S100B neurons. (J:82129)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:82129 Vives V, et al., Visualization of S100B-positive neurons and glia in the central nervous system of EGFP transgenic mice. J Comp Neurol. 2003 Mar 17;457(4):404-19
• All: 6 reference(s)