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Tg(MMTV-Espl1)1Pati
Transgene Detail
Summary
Symbol: Tg(MMTV-Espl1)1Pati
Name: transgene insertion 1, Debananda Pati
MGI ID: MGI:5637741
Transgene: Tg(MMTV-Espl1)1Pati  Location: unknown  
Alliance: Tg(MMTV-Espl1)1Pati page
Transgene
origin
Strain of Origin:  C57BL/6
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
 
Tg(MMTV-Espl1)1Pati expresses 1 gene
 
Mutation detailsThe mouse mammary tumor virus long terminal repeats were used to drive mammary epithelium-specific expression of the full-length mouse Espl1 cDNA. Western blot and immunofluorescence confirmed expression in mammary glands of adult females at day 5 of lactation. Four lines were generated but two (Tg1 and Tg2) were used for studies. (J:216267)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:216267 Mukherjee M, et al., MMTV-Espl1 transgenic mice develop aneuploid, estrogen receptor alpha (ERalpha)-positive mammary adenocarcinomas. Oncogene. 2014 Nov 27;33(48):5511-22
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/12/2024
MGI 6.23
The Jackson Laboratory