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Tg(tetO-SNCA)0Olri
Transgene Detail
Summary
Symbol: Tg(tetO-SNCA)0Olri
Name: transgene insertion 0, Olaf Riess
MGI ID: MGI:5512701
Synonyms: alpha-syn
Transgene: Tg(tetO-SNCA)0Olri  Location: unknown  
Alliance: Tg(tetO-SNCA)0Olri page
Transgene
origin
Strain of Origin:  Not Specified
Transgene
description
Transgene Type:    Transgenic (Humanized sequence, Inducible, Inserted expressed sequence)
Inducer:    doxycycline/tetracycline
Mutation:    Insertion
 
Tg(tetO-SNCA)0Olri expresses 1 gene
 
Mutation detailsThis transgene consists of the human alpha-synuclein cDNA (nucleotides 46-520) downstream of the tet-responsive element. Two lines were made: alpha-syn and alpha-syn1. This line is the one referred to as alpha-syn. (J:132774)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:132774 Nuber S, et al., Neurodegeneration and motor dysfunction in a conditional model of Parkinson's disease. J Neurosci. 2008 Mar 5;28(10):2471-84
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/12/2024
MGI 6.23
The Jackson Laboratory