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Rr20 Other Genome Feature Detail
Summary
  • Symbol
    Rr20
  • Name
    regulatory region 20
  • Synonyms
    ECR5
  • Feature Type
    unclassified other genome feature
  • IDs
    MGI:5441844
Location & Maps
less
  • Sequence Map
    Genome coordinates not available
  • Genetic Map
    Chromosome 11, Syntenic
Human Diseases
more
  • Diseases
    1 with Rr20 mouse models

Human Disease Mouse Models
       Hyperostosis Corticalis Generalisata   OMIM: 239100 View 1 model
Click on a disease name to see all genes associated with that disease.

  • Mutations/Alleles
    1 with disease annotations
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    9 phenotypes from 1 allele in 1 genetic background
    1 images
    1 phenotype reference
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    1
  • Targeted
    1
Mice homozygous for a knock-out allele exhibit reduced and variable expression of Sost with increased bone formation and bone mass.
References
more
  • Summaries
    All 1
    Diseases 1
    Phenotypes 1
  • Earliest
    J:188586 Collette NM, et al., Targeted deletion of Sost distal enhancer increases bone formation and bone mass. Proc Natl Acad Sci U S A. 2012 Aug 28;109(35):14092-7

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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Funding Information
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last database update
09/20/2016
MGI 6.05
The Jackson Laboratory