Rr20
Other Genome Feature Detail

Symbol Name ID

Rr20 regulatory region 20 MGI:5441844

Feature Type

unclassified other genome feature

Genetic Map

Chromosome 11
Syntenic

Alleles and phenotypes

All alleles(1) : Targeted(1)
 

Mice homozygous for a knock-out allele exhibit reduced and variable expression of Sost with increased bone formation and bone mass.

 
Human Diseases Modeled Using Mouse Rr20 (1)    Alleles Annotated to Human Diseases(1)   

References

(Earliest) J:188586 Collette NM, et al., Targeted deletion of Sost distal enhancer increases bone formation and bone mass. Proc Natl Acad Sci U S A. 2012 Aug 28;109(35):14092-7
All references(1)