Tg(H2-Dd/H2-Ld)DL1Ul
Transgene Detail
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Symbol: |
Tg(H2-Dd/H2-Ld)DL1Ul |
Name: |
transgene insertion DL1, Urban Lendahl |
MGI ID: |
MGI:5305234 |
Synonyms: |
DL1, T62UL, Tg(H2Dd alfa1/H2Dd alfa2/H2Dd alfa3)DL1 |
Transgene: |
Tg(H2-Dd/H2-Ld)DL1Ul Location: unknown
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Alliance: |
Tg(H2-Dd/H2-Ld)DL1Ul page
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Transgene Type: |
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Transgenic (Inserted expressed sequence) |
Mutation: |
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Insertion
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Tg(H2-Dd/H2-Ld)DL1Ul expresses
2 genes
Transgene expresses:
Organism |
Expressed Gene |
Note |
mouse |
H2-D (MGI:1933561) |
Transgene codes for a fusion protein of H2-D and H2-L. |
mouse |
H2-L (MGI:95912) |
Transgene codes for a fusion protein of H2-D and H2-L. |
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Mutation details: This transgene contains mouse genomic DNA encoding a chimeric major histocompatibility type I (MHC1) molecule comprising the alpha1 and alpha2 domains of the H2-Dd molecule joined to the alpha3, transmembrane and cytoplasmic domains of H2-Ld.
(J:180044)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 1 strain available
Cell Lines: 0 lines available
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Original: |
J:180044 Sentman CL, et al., H-2 allele-specific protection from NK cell lysis in vitro for lymphoblasts but not tumor targets. Protection mediated by alpha 1/alpha 2 domains. J Immunol. 1994 Dec 15;153(12):5482-90 |
All: |
2 reference(s) |
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