Tg(MMTV-ERBB2*,-luc)6157Aami
Transgene Detail
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Symbol: |
Tg(MMTV-ERBB2*,-luc)6157Aami |
Name: |
transgene insertion 6157, Augusto Amici |
MGI ID: |
MGI:5013830 |
Synonyms: |
delta16HER2-LUC, Tg(delta16HER2-LUC)6157Acam |
Transgene: |
Tg(MMTV-ERBB2*,-luc)6157Aami Location: unknown
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Alliance: |
Tg(MMTV-ERBB2*,-luc)6157Aami page
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Tg(MMTV-ERBB2*,-luc)6157Aami/0 mice develop spontaneous mammary tumors
Show the 2 phenotype image(s) involving this allele.
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Transgene Type: |
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Transgenic (Humanized sequence, Inserted expressed sequence, Reporter) |
Mutation: |
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Insertion
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Tg(MMTV-ERBB2*,-luc)6157Aami expresses
1 gene
Transgene expresses:
Organism |
Expressed Gene |
Homolog in Mouse |
Note |
human |
ERBB2 (2064) |
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Mutation details: The MMTV promoter drives mammary gland-specific expression of human ERBB2 with an in-frame deletion of exon 16 (variant identified in human breast carcinomas) and an IRES-luciferase. Lines 6157, 6177, and 6180 were generated.
(J:172352)
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Schematic representation of Tg(MMTV-ERBB2*,-luc)6157Aami |
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Original: |
J:172352 Marchini C, et al., The Human Splice Variant Delta16HER2 Induces Rapid Tumor Onset in a Reporter Transgenic Mouse. PLoS One. 2011;6(4):e18727 |
All: |
8 reference(s) |
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