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Tg(Tert-GFP)22Brlt
Transgene Detail
Summary
Symbol: Tg(Tert-GFP)22Brlt
Name: transgene insertion 22, David T Breault
MGI ID: MGI:4941636
Synonyms: mTert-GFP
Transgene: Tg(Tert-GFP)22Brlt  Location: unknown  
Alliance: Tg(Tert-GFP)22Brlt page
Transgene
origin
Germline Transmission:  Earliest citation of germline transmission: J:139017
Parent Cell Line:  J1 (ES Cell)
Strain of Origin:  129S4/SvJae
Transgene
description
Transgene Type:    Transgenic (Reporter)
Mutation:    Insertion
 
Mutation detailsA 4471 kb fragment of the mouse telomerase reverse transcriptase (Tert) gene was used to drive expression of GFP in the construct. The construct was electroporated into J1 ES cells that were screened and selected for GFP expression. Transgenic mice were generated by standard methods from ES cells showing transgene expression. Lines 14 and 22 were analyzed extensively and demonstrated similar GFP expression patterns. Detailed analysis for line 22 was presented. (J:139017, J:169663)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:139017 Breault DT, et al., Generation of mTert-GFP mice as a model to identify and study tissue progenitor cells. Proc Natl Acad Sci U S A. 2008 Jul 29;105(30):10420-5
All:  7 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory