Tg(Tert-GFP)22Brlt
Transgene Detail
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Symbol: |
Tg(Tert-GFP)22Brlt |
Name: |
transgene insertion 22, David T Breault |
MGI ID: |
MGI:4941636 |
Synonyms: |
mTert-GFP |
Transgene: |
Tg(Tert-GFP)22Brlt Location: unknown
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Alliance: |
Tg(Tert-GFP)22Brlt page
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Germline Transmission: |
Earliest citation of germline transmission:
J:139017
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Parent Cell Line: |
J1 (ES Cell)
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Strain of Origin: |
129S4/SvJae
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Transgene Type: |
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Transgenic (Reporter) |
Mutation: |
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Insertion
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Mutation details: A 4471 kb fragment of the mouse telomerase reverse transcriptase (Tert) gene was used to drive expression of GFP in the construct. The construct was electroporated into J1 ES cells that were screened and selected for GFP expression. Transgenic mice were generated by standard methods from ES cells showing transgene expression. Lines 14 and 22 were analyzed extensively and demonstrated similar GFP expression patterns. Detailed analysis for line 22 was presented.
(J:139017, J:169663)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Original: |
J:139017 Breault DT, et al., Generation of mTert-GFP mice as a model to identify and study tissue progenitor cells. Proc Natl Acad Sci U S A. 2008 Jul 29;105(30):10420-5 |
All: |
7 reference(s) |
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