Tg(tetO/CMV-Lck)1Rza
Transgene Detail

Summary

• Symbol: Tg(tetO/CMV-Lck)1Rza
• Name: transgene insertion 1, Rose Zamoyska
• MGI ID: MGI:3806710
• Transgene: Tg(tetO/CMV-Lck)1Rza Location: unknown
• Alliance: Tg(tetO/CMV-Lck)1Rza page

Transgene origin

• Strain of Origin: (CBA x C57BL/10)F2

Transgene description

• Transgene Type: Transgenic (Inducible, Inserted expressed sequence)
• Inducer: doxycycline/tetracycline
• Mutation: Insertion
• Mutation details: A mouse cDNA for Lck was placed downstream of the tetO/CMV promoter. Three lines were produced. Line 1 is entered as the representative line. (J:110527)

Tumor Data

List all tumor models in MMHCdb carrying Tg(tetO/CMV-Lck)1Rza

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:110527 Legname G, et al., Inducible expression of a p56Lck transgene reveals a central role for Lck in the differentiation of CD4 SP thymocytes. Immunity. 2000 May;12(5):537-46
• All: 10 reference(s)