About   Help   FAQ
Tg(MMTV-LPAR1)27Gbm
Transgene Detail
Summary
Symbol: Tg(MMTV-LPAR1)27Gbm
Name: transgene insertion 27, Gordon B Mills
MGI ID: MGI:4835232
Synonyms: LPA1-L27
Transgene: Tg(MMTV-LPAR1)27Gbm  Location: unknown  
Alliance: Tg(MMTV-LPAR1)27Gbm page
Transgene
origin
Strain of Origin:  FVB/N
Transgene
description
Transgene Type:    Transgenic (Epitope tag, Humanized sequence, Inserted expressed sequence)
Mutation:    Insertion
 
Tg(MMTV-LPAR1)27Gbm expresses 1 gene
 
Mutation detailsThe MMTV-lpa1 transgenic construct contains the 1.54 kb MMTV LTR and the full-length cDNA of FLAG-tagged human LPA1 receptor linked to the KCR fragment containing the exon II (E2), intron II (I2), exon III (E3), and polyadenylation signal (rbGpA) derived from rabbit beta-globin. Three MMTV-lpa1 (#LPA1-2, #LPA1-7, and #LPA1-27) founders passed the transgene through the germ line. (J:149661)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Disease models
Loading...
Tumor Data
List all tumor models in MMHCdb carrying Tg(MMTV-LPAR1)27Gbm
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:149661 Liu S, et al., Expression of autotaxin and lysophosphatidic acid receptors increases mammary tumorigenesis, invasion, and metastases. Cancer Cell. 2009 Jun 2;15(6):539-50
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
03/12/2024
MGI 6.23
The Jackson Laboratory