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Ppcd1 Other Genome Feature Detail
Summary
  • Symbol
    Ppcd1
  • Name
    posterior polymorphous corneal dystrophy 1
  • Synonyms
    Dp(2Csrp2bp-6330439K17Rik)1Bra, Dp(2Csrp2bp-Dzank1)1Bra, PPCD1
  • Feature Type
    mutation defined region
  • IDs
    MGI:4830884
Location &
Maps
less
  • Sequence Map
    Genome coordinates not available
  • Genetic Map
    Chromosome 2, Syntenic
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    17 phenotypes from 1 allele in 4 genetic backgrounds
    2 phenotypes from multigenic genotypes
    3 images
    3 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Mice heterozygous for the mutation exhibit abnormal cornea and preweaning lethality.
References
more
  • Summaries
    All 4
    Phenotypes 3
  • Earliest
    J:164007 Shen AL, et al., The PPCD1 mouse: characterization of a mouse model for posterior polymorphous corneal dystrophy and identification of a candidate gene. PLoS One. 2010;5(8)
  • Latest
    J:251676 Shen AL, et al., Retinal pathology in the PPCD1 mouse. PLoS One. 2017;12(10):e0185094

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/23/2021
MGI 6.17
The Jackson Laboratory