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Del(14Trim13-Dleu2)4Rdf Cytogenetic Marker Detail
Summary
  • Symbol
    Del(14Trim13-Dleu2)4Rdf
  • Name
    deletion, Chr 14, Riccardo Dalla-Favera 4
  • Synonyms
    MDR-
  • Feature Type
    chromosomal deletion
  • IDs
    MGI:4437007
Location & Maps
more
  • Genetic Map
    Chromosome 14, Syntenic
Human Diseases
more
  • Diseases
    1 with Del(14Trim13-Dleu2)4Rdf mouse models

Human Disease Mouse Models
       Leukemia, Chronic Lymphocytic; CLL   OMIM: 151400 View 2 models
Click on a disease name to see all genes associated with that disease.

  • Mutations/Alleles
    1 with disease annotations
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    8 phenotypes from 1 allele in 1 genetic background
    5 phenotypes from multigenic genotypes
    3 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    1
  • Targeted
    1
References
more
  • Summaries
    All 4
    Diseases 1
    Phenotypes 3
  • Earliest
    J:156946 Klein U, et al., The DLEU2/miR-15a/16-1 Cluster Controls B Cell Proliferation and Its Deletion Leads to Chronic Lymphocytic Leukemia. Cancer Cell. 2010 Jan 19;17(1):28-40
  • Latest
    J:178933 Kasinski AL, et al., Epigenetics and genetics. MicroRNAs en route to the clinic: progress in validating and targeting microRNAs for cancer therapy. Nat Rev Cancer. 2011;11(12):849-64

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/29/2016
MGI 6.06
The Jackson Laboratory