Tg(Csf1r-EGFP)1Hume
Transgene Detail

Summary

• Symbol: Tg(Csf1r-EGFP)1Hume
• Name: transgene insertion 1, David A Hume
• MGI ID: MGI:4420302
• Synonyms: 7.2fms-EGFP, c-fms-EGFP, Csf1r-EGFP, MacGreen, Tg(Csf1r-Gfp)Hume
• Transgene: Tg(Csf1r-EGFP)1Hume Location: unknown
• Alliance: Tg(Csf1r-EGFP)1Hume page

Transgene origin

• Strain of Origin: (C57BL/6 x CBA)F1

Transgene description

• Transgene Type: Transgenic (Reporter)
• Mutation: Insertion
• Mutation details: The construct had 3.5 kb of sequence flanking exon 2 and the entire intron 2 sequence of the Csf1r gene driving expression of EGFP. This construct was injected into pronuclei of (C57BL/6 x CBA)F1 fertilized eggs. 5 lines that transmitted the transgene were generated, and EGFP expression was readily detected in peritoneal, bone marrow-derived, and broncho-alveolar lavage macrophages from all lines. (J:156311)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:156311 Sasmono RT, et al., A macrophage colony-stimulating factor receptor-green fluorescent protein transgene is expressed throughout the mononuclear phagocyte system of the mouse. Blood. 2003 Feb 1;101(3):1155-63
• All: 76 reference(s)