Tg(Eno2-cre)#Lfp
Transgene Detail

Summary

• Symbol: Tg(Eno2-cre)#Lfp
• Name: transgene insertion, Luis F Parada
• MGI ID: MGI:4367263
• Synonyms: Nse-cre, Tg(Eno2-cre)Lfp
• Transgene: Tg(Eno2-cre)#Lfp Location: unknown
• Alliance: Tg(Eno2-cre)#Lfp page

Transgene origin

• Strain of Origin: FVB/NJ

Transgene description

• Transgene Type: Transgenic (Recombinase)
• Mutation: Insertion
• Tg(Eno2-cre)#Lfp expression driven by 1 gene
  Transgene expression driven by:
  

  Organism

  Driver Gene

  Homolog in Mouse

  Note

  rat

  Eno2 (24334)

  Eno2	(MGI:95394)

• Mutation details: The rat enolase 2, gamma neuronal promoter was used to drive expression of cre recombinase in most neurons and neuroendocrine cells. Two founder lines, CK1 and CK2, were obtained and hybridization analyses with a cre probe showed that each line arose from independent transgene insertions. The pound symbol (#) is used when no line is specified and/or lines are pooled. (J:106767)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Eno2 (rat) Summary of all recombinase alleles driven by Eno2. Alliance rat Eno2 gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:153717 Zhou J, et al., Loss of Tsc1, but not Pten, in renal tubular cells causes polycystic kidney disease by activating mTORC1. Hum Mol Genet. 2009 Nov 15;18(22):4428-41
• All: 4 reference(s)