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Tg(APOE-MBOAT4)1Jagu
Transgene Detail
Summary
Symbol: Tg(APOE-MBOAT4)1Jagu
Name: transgene insertion 1, Jesus A Gutierrez
MGI ID: MGI:4354173
Transgene: Tg(APOE-MBOAT4)1Jagu  Location: unknown  
Alliance: Tg(APOE-MBOAT4)1Jagu page
Transgene
origin
Strain of Origin:  Not Specified
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
 
Tg(APOE-MBOAT4)1Jagu expresses 1 gene
 
Mutation detailsA C-terminal Flag-tagged version of the human gene was cloned with the addition of a 5' Kozak sequence into a transgene vector driven by the human apoE gene promoter and its hepatic control region for specific liver tissue expression. Functional expression of the transgene was determined by blood ghrelin immunoprecipitation matrix-assisted laser desorption-ionization-time-of-flight mass spectometry analyses. (J:151420)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:151420 Kirchner H, et al., GOAT links dietary lipids with the endocrine control of energy balance. Nat Med. 2009 Jul;15(7):741-5
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory