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Tg(ACTA1-Capn3*)10.3Spc
Transgene Detail
Summary
Symbol: Tg(ACTA1-Capn3*)10.3Spc
Name: transgene insertion 10.3, Melissa J Spencer
MGI ID: MGI:3839626
Transgene: Tg(ACTA1-Capn3*)10.3Spc  Location: unknown  
Alliance: Tg(ACTA1-Capn3*)10.3Spc page
Transgene
origin
Strain of Origin:  (C57BL/6J x BALB/c)F2
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
 
Tg(ACTA1-Capn3*)10.3Spc expresses 1 gene
 
Mutation detailsA construct with the human skeletal alpha actin promoter driving the mouse calpain 3 sequence lacking exon 15, thereby removing the IS2 domain, was microinjected into (C57BL/6J x BALB/c)F2 oocytes and integrated via random insertion. (J:77348)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:77348 Spencer MJ, et al., Stable expression of calpain 3 from a muscle transgene in vivo: immature muscle in transgenic mice suggests a role for calpain 3 in muscle maturation. Proc Natl Acad Sci U S A. 2002 Jun 25;99(13):8874-9
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory