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Tc(HSA21)1TybEmcf Other Genome Feature Detail
Summary
  • Symbol
    Tc(HSA21)1TybEmcf
  • Name
    transchromosomal, human 21, line 1, Victor Tybulewicz and Elizabeth M C Fisher
  • Synonyms
    Tc(HSA21)91-1Emcf
  • Feature Type
    unclassified other genome feature
  • IDs
    MGI:3814702
Location & Maps
less
  • Sequence Map
    Genome coordinates not available
  • Genetic Map
    Chromosome Unknown
Human Diseases
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  • Diseases
    1 with Tc(HSA21)1TybEmcf mouse models

Human Disease Mouse Models
       Down Syndrome   OMIM: 190685 View 1 model
Click on a disease name to see all genes associated with that disease.

  • Mutations/Alleles
    1 with disease annotations
  • References
    6 with disease annotations
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    17 phenotypes from 1 allele in 2 genetic backgrounds
    8 phenotypes from multigenic genotypes
    19 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryogenesis
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
tumorigenesis
vision/eye

Click cells to view annotations.
References
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  • Summaries
    All 20
    Diseases 6
    Phenotypes 19
  • Earliest
    J:101383 O'Doherty A, et al., An aneuploid mouse strain carrying human chromosome 21 with Down syndrome phenotypes. Science. 2005 Sep 23;309(5743):2033-7
  • Latest
    J:228970 Cloutier JM, et al., Histone H2AFX Links Meiotic Chromosome Asynapsis to Prophase I Oocyte Loss in Mammals. PLoS Genet. 2015 Oct;11(10):e1005462

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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Funding Information
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last database update
04/26/2016
MGI 6.03
The Jackson Laboratory