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Tg(Alb1-Plau)144Bri
Transgene Detail
Summary
Symbol: Tg(Alb1-Plau)144Bri
Name: transgene insertion 144, Ralph Brinster
MGI ID: MGI:3802778
Synonyms: line 1353-8, Tg(Alb-1,Plau)Bri144
Transgene: Tg(Alb1-Plau)144Bri  Location: unknown  
Alliance: Tg(Alb1-Plau)144Bri page
Transgene
origin
Strain of Origin:  Not Specified
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
 
Tg(Alb1-Plau)144Bri expresses 1 gene
 
Mutation detailsThe murine albumin enhancer/promoter drives expression of a murine urokinase plasminogen aactivator (Plau) gene. Expression of transgene-derived mRNA is detected at high levels in the liver, and zymogen assays show an increased level of Plau activity in plasma derived from transgenic mice. (J:135419)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:135419 Heckel JL, et al., Neonatal bleeding in transgenic mice expressing urokinase-type plasminogen activator. Cell. 1990 Aug 10;62(3):447-56
All:  10 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory