About   Help   FAQ
Tg(Pdgfb-icre/ERT2,-EGFP)1Frut
Transgene Detail
Summary
Symbol: Tg(Pdgfb-icre/ERT2,-EGFP)1Frut
Name: transgene insertion 1, Marcus Fruttiger
MGI ID: MGI:3793852
Synonyms: Pdgfb-iCreER, Pdgfb-iCre-ERT2-Egfp, Tg(Pdgfb-cre/ERT2)1Frut, Tg(Pdgfb-cre/ESR1)1Frut
Transgene: Tg(Pdgfb-icre/ERT2,-EGFP)1Frut  Location: unknown  
Alliance: Tg(Pdgfb-icre/ERT2,-EGFP)1Frut page
Transgene
origin
Strain of Origin:  (C57BL/6 x CBA)F2
Transgene
description
Transgene Type:    Transgenic (Inducible, Recombinase)
Inducer:    tamoxifen
Mutation:    Insertion
 
Tg(Pdgfb-icre/ERT2,-EGFP)1Frut expression driven by 1 gene
 
Mutation detailsThe mouse Pdgfb promoter was used to drive inducible expression of an improved cre gene fused to ERT2 and followed by an IRES-EGFP then an frt-flanked chloramphenicol resistance gene in vascular endothelium. The PAC used (RP21-629-J8) contains the entire Pdgfb gene with the cre cassette inserted immediately following the start methionine codon. No line information was given. (J:135315)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Pdgfb (mouse)
Summary of all recombinase alleles driven by Pdgfb.
 

Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Disease models
Loading...
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:135315 Claxton S, et al., Efficient, inducible Cre-recombinase activation in vascular endothelium. Genesis. 2008 Feb;46(2):74-80
All:  152 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
03/19/2024
MGI 6.23
The Jackson Laboratory