About   Help   FAQ
Mirc1
Complex/Cluster/Region Detail
 Symbol
Name
ID
Cluster members
Mirc1
microRNA cluster 1, including Mir17 through Mir92-1
MGI:3790484
Mir17, Mir18, Mir19a ... (6 members)
Synonyms miR-17~92, miR-17-92, Mir17-92, Mirn17-92
Feature Type complex/cluster/region
Genetic Map
Chromosome 14
Syntenic

Mapping data(1)
Sequence Map
Chr14:115043671-115044506 bp
From MGI annotation of GRCm38

  836 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Mutations,
alleles, and
phenotypes
All mutations/alleles(5) : Targeted(5)
 
Homozygous deletion of this Mirn cluster results in neonatal lethality. Lung hypoplasia is observed in late gestation and newborn mice; fetal and adult B cell development are compromised also.
 
Human Diseases Modeled Using Mouse Mirc1 (1)    Alleles Annotated to Human Diseases(1)   
Expression
Literature Summary: (3 records)
Other database
links
miRBaseMI0000567, MI0000568, MI0000687, MI0000688, MI0000718, MI0000719
Polymorphisms SNPs within 2kb(5 from dbSNP Build 137)
References (Earliest) J:105741 Griffiths-Jones S, et al., miRBase: microRNA sequences, targets and gene nomenclature. Nucleic Acids Res. 2006 Jan 1;34(Database issue):D140-4
(Latest) J:207787 Olive V, et al., A component of the mir-17-92 polycistronic oncomir promotes oncogene-dependent apoptosis. Elife. 2013;2:e00822
All references(32)
Disease annotation references (1)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
09/09/2014
MGI 5.19
The Jackson Laboratory