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Mirc1
Complex/Cluster/Region Detail
Symbol

Name
ID
Cluster members
Mirc1
microRNA cluster 1, including Mir17 through Mir92-1
MGI:3790484
Mir17, Mir18, Mir19a ... (6 members)
Synonyms
miR-17~92, miR-17-92, Mir17-92, Mirn17-92
Feature Type
complex/cluster/region
Genetic Map
Chromosome 14
Syntenic

Mapping data(1)
Sequence Map
Chr14:115043671-115044506 bp
From MGI annotation of GRCm38

  836 bp   ±  kb flank

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Mouse Genome Browser
Mutations,
alleles, and
phenotypes
All mutations/alleles(9) : Targeted(9)
 
Homozygous deletion of this Mirn cluster results in neonatal lethality. Lung hypoplasia is observed in late gestation and newborn mice; fetal and adult B cell development are compromised also.
 
Human Diseases Modeled in Mice Using Mirc1 (1)    Mutations Annotated to Human Diseases (1)   
Expression
Literature Summary: (3 records)
Other database
links
Polymorphisms
SNPs within 2kb(5 from dbSNP Build 137)
References
(Earliest) J:105741 Griffiths-Jones S, et al., miRBase: microRNA sequences, targets and gene nomenclature. Nucleic Acids Res. 2006 Jan 1;34(Database issue):D140-4
(Latest) J:223213 Han YC, et al., An allelic series of miR-17 approximately 92-mutant mice uncovers functional specialization and cooperation among members of a microRNA polycistron. Nat Genet. 2015 Jul;47(7):766-75
All references(39)
Disease annotation references (1)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/18/2015
MGI 6.0
The Jackson Laboratory