Tg(Eno2-EGFP/cre)25kb2Ngc
Transgene Detail

Summary

• Symbol: Tg(Eno2-EGFP/cre)25kb2Ngc
• Name: transgene insertion 25kb2, Neal G Copeland
• MGI ID: MGI:3783336
• Transgene: Tg(Eno2-EGFP/cre)25kb2Ngc Location: unknown
• Alliance: Tg(Eno2-EGFP/cre)25kb2Ngc page

Transgene origin

• Strain of Origin: (C3H/HeN x C57BL/6NCr)F2

Transgene description

• Transgene Type: Transgenic (Recombinase)
• Mutation: Insertion
• Tg(Eno2-EGFP/cre)25kb2Ngc expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Eno2 (MGI:95394)

• Mutation details: The transgene consists of a 25 Kb fragment from BAC 284H12, that contains mouse Eno2 driving neural-specific expression of an IRES-EGFP-cre cassette, which was inserted into the last exon of the locus. Two lines were created with neural cre expression in different subsets of neurons. This line contains 5 copies of the transgene and is expressed in most basket cells, stellae cells, Purkinjie cells and neurons of the deep cerebellar nuclei but few granule cells and Golgi cells in the granule layer (J:133505)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Eno2 (mouse) Summary of all recombinase alleles driven by Eno2. Comparative matrix view of recombinase activities Alliance mouse Eno2 gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:133505 Lee EC, et al., A highly efficient Escherichia coli-based chromosome engineering system adapted for recombinogenic targeting and subcloning of BAC DNA. Genomics. 2001 Apr 1;73(1):56-65
• All: 1 reference(s)