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Tg(Alb1HBV)43Bri
Transgene Detail
Summary
Symbol: Tg(Alb1HBV)43Bri
Name: transgene insertion 43, Ralph L Brinster
MGI ID: MGI:3510558
Synonyms: 45-2, 45.2, Tg(Alb-1HBV)Bri43, Tg(Alb1-HBVL)43Bri
Transgene: Tg(Alb1HBV)43Bri  Location: unknown  
Alliance: Tg(Alb1HBV)43Bri page
Transgene
origin
Strain of Origin:  (C57BL/6 x SJL)F1
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
 
Mutation detailsThe mouse albumin promoter was used to drive high levels of hepatitis B virus large envelope gene expression in hepatocytes. Approximately 40-50% of hepatocytes expressed the transgene in an area limited to the periphery of the hepatic lobule. (J:86165)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 1 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:86165 Chisari FV, et al., Molecular pathogenesis of hepatocellular carcinoma in hepatitis B virus transgenic mice. Cell. 1989 Dec 22;59(6):1145-56
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory