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plt
Gene Detail
 Symbol
Name
ID
plt
paucity of lymph node T cells
MGI:3664332
Feature Type heritable phenotypic marker
Genetic Map
Chromosome 4
Syntenic
Mutations,
alleles, and
phenotypes
All mutations/alleles(1) : Spontaneous(1)
 
In homozygous mutant mice, naive T cells fail to localize in the lymph nodes or in the lymphoid regions of the spleen.
 
Human Diseases Modeled Using Mouse plt (1)    Alleles Annotated to Human Diseases(1)   
References (Earliest) J:15290 Nakano H, et al., Nonspecific augmentation of lymph node T cells and I-E-independent selective deletion of V beta 14+ T cells by Mtv-2 in the DDD mouse. Eur J Immunol. 1993 Oct;23(10):2434-9
(Latest) J:204815 Obata T, et al., Critical role of dendritic cells in T cell retention in the interfollicular region of Peyer's patches. J Immunol. 2013 Jul 15;191(2):942-8
All references(68)
Disease annotation references (1)

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/19/2014
MGI 5.19
The Jackson Laboratory