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plt Gene Detail
Summary
  • Symbol
    plt
  • Name
    paucity of lymph node T cells
  • Feature Type
    heritable phenotypic marker
  • IDs
    MGI:3664332
Location & Maps
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  • Sequence Map
    Genome coordinates not available
  • Genetic Map
    Chromosome 4, Syntenic
Human Diseases
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  • Diseases
    1 with plt mouse models

Human Disease Mouse Models
       Sjogren Syndrome   OMIM: 270150 View 1 model
Click on a disease name to see all genes associated with that disease.

  • Mutations/Alleles
    1 with disease annotations
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    30 phenotypes from 1 allele in 4 genetic backgrounds
    68 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryogenesis
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
tumorigenesis
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    1
  • Spontaneous
    1
In homozygous mutant mice, naive T cells fail to localize in the lymph nodes or in the lymphoid regions of the spleen.
References
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  • Summaries
    All 69
    Diseases 1
    Phenotypes 68
  • Earliest
    J:15290 Nakano H, et al., Nonspecific augmentation of lymph node T cells and I-E-independent selective deletion of V beta 14+ T cells by Mtv-2 in the DDD mouse. Eur J Immunol. 1993 Oct;23(10):2434-9
  • Latest
    J:204815 Obata T, et al., Critical role of dendritic cells in T cell retention in the interfollicular region of Peyer's patches. J Immunol. 2013 Jul 15;191(2):942-8

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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Funding Information
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last database update
01/26/2016
MGI 6.02
The Jackson Laboratory