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plt
Gene Detail
Symbol

Name
ID
plt
paucity of lymph node T cells
MGI:3664332
Feature Type
heritable phenotypic marker
Genetic Map
Chromosome 4
Syntenic
Mutations,
alleles, and
phenotypes
All mutations/alleles(1) : Spontaneous(1)
 
In homozygous mutant mice, naive T cells fail to localize in the lymph nodes or in the lymphoid regions of the spleen.
 
Human Diseases Modeled in Mice Using plt (1)    Mutations Annotated to Human Diseases (1)   
References
(Earliest) J:15290 Nakano H, et al., Nonspecific augmentation of lymph node T cells and I-E-independent selective deletion of V beta 14+ T cells by Mtv-2 in the DDD mouse. Eur J Immunol. 1993 Oct;23(10):2434-9
(Latest) J:204815 Obata T, et al., Critical role of dendritic cells in T cell retention in the interfollicular region of Peyer's patches. J Immunol. 2013 Jul 15;191(2):942-8
All references(68)
Disease annotation references (1)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
06/23/2015
MGI 5.22
The Jackson Laboratory