plt
Gene Detail

Symbol Name ID

plt paucity of lymph node T cells MGI:3664332

Feature Type

heritable phenotypic marker

Genetic Map

Chromosome 4
Syntenic

Alleles and phenotypes

All alleles(1) : Spontaneous(1)
 

In homozygous mutant mice, naive T cells fail to localize in the lymph nodes or in the lymphoid regions of the spleen.

 
Human Diseases Modeled Using Mouse plt (1)    Alleles Annotated to Human Diseases(1)   

References

(Earliest) J:15290 Nakano H, et al., Nonspecific augmentation of lymph node T cells and I-E-independent selective deletion of V beta 14+ T cells by Mtv-2 in the DDD mouse. Eur J Immunol. 1993 Oct;23(10):2434-9
(Latest) J:188949 Umemoto E, et al., Constitutive plasmacytoid dendritic cell migration to the splenic white pulp is cooperatively regulated by CCR7- and CXCR4-mediated signaling. J Immunol. 2012 Jul 1;189(1):191-9
All references(63)