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Tg(ITGAM-cre)2781Gkl
Transgene Detail
Summary
Symbol: Tg(ITGAM-cre)2781Gkl
Name: transgene insertion 2781, George Kollias
MGI ID: MGI:3629092
Synonyms: CD11b-Cre, Tg(ITGAM-cre)1Dwc
Transgene: Tg(ITGAM-cre)2781Gkl  Location: unknown  
Alliance: Tg(ITGAM-cre)2781Gkl page
Transgene
origin
Strain of Origin:  (CBA x C57BL/6)F1
Transgene
description
Transgene Type:    Transgenic (Recombinase)
Mutation:    Insertion
 
Tg(ITGAM-cre)2781Gkl expression driven by 1 gene
 
Mutation detailsA 1.7 kb DNA fragment of the human integrin alpha M promoter was used to drive expression of cre recombinase in the myeloid lineage. (J:109131)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: ITGAM (human)
Summary of all recombinase alleles driven by ITGAM.
 

Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Expression
In Mice Carrying this Mutation: 1 RNA-Seq or microarray experiment(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
References
Original:  J:109131 Boillee S, et al., Onset and Progression in Inherited ALS Determined by Motor Neurons and Microglia. Science. 2006 Jun 2;312(5778):1389-92
All:  26 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory